精神心理因素在肠易激综合征中的作用  

Effects of Psychological Factors on Irritable Bowel Syndrome

作　　者：曹佳懿[1] 侯晓华[2] 

机构地区：[1]武汉钢铁集团公司职工总医院消化内科,430080 [2]华中科技大学同济医学院附属协和医院消化科

出　　处：《胃肠病学》2008年第2期121-124,共4页Chinese Journal of Gastroenterology

摘　　要：精神心理因素异常是肠易激综合征(IBS)的发病机制之一,但其具体机制尚未完全明了。多数研究发现IBS患者伴随不同程度和类型的精神心理异常,经历过更多的负性生活事件,表现出一些异常的行为特征,但各地的研究结论存有一定差异。目前的研究多集中于精神心理异常是如何改变脑-肠轴的功能,从而参与IBS的发生、发展。在IBS的治疗中,精神药物和心理疗法都表现出一定的作用,但不是决定性的,其疗效尚需更多的循证医学证据来证明。Abnormal psychological factors are involved in the pathogenesis of irritable bowel syndrome （IBS）, but its mechanism is still not completely clear. Many studies have demonstrated that IBS patients are accompanied by different grades and types of psychological disturbances, experience more negative life events, and show some abnormal behavior characteristics, however, some differences have been found in the conclusions of various studies. Current researches focus mostly on how abnormal psychological factors change the function of brain-gut axis, thereby participate in the development of IBS. Psychotropic drugs and psychotherapy do have some effects on the treatment of IBS, but not the determinant one, and more evidences on the basis of the evidence-based medicine are needed to prove it.

关 键 词：肠易激综合征 精神心理因素 生活变动事件 精神治疗药物 心理疗法 

分 类 号：R574[医药卫生—消化系统]