晚期胰腺癌^(125)Ⅰ粒子植入术后并发胃瘫综合征的临床观察与护理  

Clinical Observation and Nursing Care of Postoperative Gastroparesis Syndrome after Iodine-125 Brachytherapy for Unresectable Pancreas Cancer

作　　者：王丽芹[1] 李慧琼[1] 赵文静[1] 李丽[1] 

机构地区：[1]解放军总医院第二附属医院肝胆外科,北京100091

出　　处：《解放军护理杂志》2008年第5期48-49,60,共3页Nursing Journal of Chinese People's Liberation Army

摘　　要：目的分析晚期胰腺癌125Ⅰ粒子植入术后并发胃瘫综合征(postoperative gastroparesis syndrome,PGS)的相关因素,从护理角度探讨预防和促进康复的有效措施。方法回顾性分析了48例不能根治切除的晚期胰腺癌病例,了解PGS发生率和不同姑息性手术术式的关系,包括粒子植入数目、位置等对发生PGS的影响。结果125Ⅰ粒子植入术病例PGS发生率高于其他手术组;随着粒子数目增加,PGS的发生率增高。结论125Ⅰ粒子植入术治疗晚期胰腺癌可导致术后发生PGS,护理人员应正确认识其发生的相关因素;严密观察病情,识别胃瘫的早期症状,及时治疗;同时,要重视患者的心理护理和发挥家庭支持作用。Objective To investigate the factors correlated to the occurrence of postoperative gastroparesis syndrome （PGS） following iodine-125 brachytherapy for unresectable pancreas cancer, and explore the countermeasures for effective prevention and nursing care intervention to promote recovery of the patients. Methods The data of 48 patients with unresectable pancreas cancer treated with different palliative operations were retrospectively reviewed. The incidence of PGS was analyzed in relation to the approaches of palliative operations, including the effect of the number of iodine-125 seeds implanted and implantation sites in iodine-125 brachytherapy. Results The incidence of PGS after iodine-125 brachytherapy was greater than that after other palliative operations, and increased number of implanted iodine-125 seeds was associated with higher PGS incidence. Conclusion Iodine-125 brachytherapy for unresectable pancreas cancer may cause potential PGS. The nurses should well recognize the factors related to PGS occurrence, closely observe the changes in the disease course and identify the early symptoms of PGS for timely interventions. Reinforced psychological nursing and full utilization of the patients＇ social support can be crucial for promoting the patients＇ early recovery.

关 键 词：胰腺癌胃瘫综合征 ^125I 观察 护理 

分 类 号：R735.9[医药卫生—肿瘤]