胃肠道恶性间质瘤的临床病理特征(附36例报告)  

Malignant Gastrointestinal Stromal Tumors:a Clinical Analysis of 36 Cases

作　　者：吴瑞乔[1] 沈新明[1] 刘良培[1] 张泽平[1] 王益[1] 严燕国[1] 

机构地区：[1]武汉科技大学附属医院普外科,湖北省武汉市430064

出　　处：《医学理论与实践》2008年第3期256-258,共3页The Journal of Medical Theory and Practice

摘　　要：目的：探讨胃肠道恶性间质瘤的临床及病理特征。方法：回顾性分析1999-2004年收治的36例胃肠道恶性间质瘤的临床及病理资料。结果：胃肠道恶性间质瘤病人的临床表现以腹痛及消化道出血为主,发生部位以小肠及胃最为常见,术后均经病理学诊断为恶性。术后复发14例,死亡4例。结论：肿瘤的大小、位置、核分裂像及免疫组化指标是判断胃肠道间质瘤良、恶性的重要指标。加强对胃肠道恶性间质瘤临床及病理特征的认识,正确的诊断及合理的手术治疗对改善其预后有着重要意义。Objective： To study the clinical manifestation and pathologic characteristics of gastrointestinal stromal tumors（GIST）. Methods： The clinical and pathological data in 36 caeses of malignant GIST admitted between 1999 and 2004 were analyzed retrospectively. Results： The common clinical manifestations were abdominal pain and digestive tract bleeding. The tumors were commonly located in the small intestine and stomach. All cases were pathologically diagnosed as malignant tumors after operation 14 cases recurred after operation and 4 cases died. Conclusion.Tumor size, location, mitosis and immunohistochemical data are important indexes for determining whether it is malignant or benign In order to improve the prognosis, it is of great importance to diagnose and treat GIST early and properly.

关 键 词：胃肠道恶性间质瘤 免疫组化 

分 类 号：R735.2[医药卫生—肿瘤] R730.262[医药卫生—临床医学]