经动脉化学性灌注和栓塞治疗晚期贲门癌32例分析  

INTRAARTERIAL CHEMOTHERAPEUTIC INFUSION AND CHEMOEMBOLIZATION THERAPY IN ADVANCED GASTRIC CANCER

作　　者：江澜[1,2] 徐德银 顾君贤 魏佳锦 曹士兵[1,2] 沈玉兰 陈桂林 施丁一 蒋华平 

机构地区：[1]中国人民武装警察部队江苏省总队医院 [2]中国癌症基金会武警分会扬州诊疗中心放射科

出　　处：《中国癌症杂志》1997年第1期34-36,共3页China Oncology

摘　　要：目的观察晚期贲门癌介入治疗的效果。方法３２例晚期贲门癌患者，采用胃动脉内化学性栓塞（ＧＡＥ）２０例，胃动脉内化学性灌注（ＧＡＩ）１２例。结果采用介入治疗，总有效率（完全缓解＋部分缓解）为８８％（２８／３２），其中ＧＡＥ组完全缓解６例。生存概率在ＧＡＥ组前５个月内，随时间推移变化不大，ＧＡＩ组３个月内迅即下降，两种方法差异有非常显著意义（Ｐ＜０．０１）。不良反应以血液学毒性为主，ＧＡＥ组合并有栓塞后综合征。结论介入治疗特别是ＧＡＥ为治疗晚期贲门癌的有效方法。PURPOSE To observe the efficacy of interventional radiology for treatment of advanced gastric cardia carcinoma. METHODS Among 32 patients, twenty were treated by chemoembolization (GAE). and twelve by chemotherapeutic infusion (GAI). RESULTS The overall effective rate was 88%. six patients achieved a complete response in the GAE group. The survival rate (Kaplan Meire) in GAI was shorter than that in GAE ( P <0 01). The major side effect was hematological toxicity. In the GAE group, patients all experienced a post embolization syndrome, but could be tolerated by the patients. CONCLUSIONS The results indicated that the two methods of management are practicable for treating advanced gastric cardiac cancer, and GAE treatment has better therapeutic effect.

关 键 词：胃肿瘤 化学栓塞 药物疗法 

分 类 号：R735.205[医药卫生—肿瘤]