间质干细胞神经分化潜能及其应用研究进展  

Potential Differentiation of Mesenchymal Stem Cells to Neuron and Research Progress of It's Application

作　　者：林长贵[1] 张志坚[1] 

机构地区：[1]福建医科大学第一临床学院神经内科,福州350005

出　　处：《医学综述》2008年第5期691-693,共3页Medical Recapitulate

基　　金：福建省自然科学基金资助项目(C0540003)

摘　　要：间质干细胞具有多分化潜能,它有多种来源,最主要来源于骨髓。间质干细胞表达大量表面标志物,但至今没有一个是非常特异的,它在体内外适当的条件下可分化为神经细胞,成为细胞组织工程理想种子,因此它可以被应用于治疗血液病、淋巴瘤和一些免疫疾病及神经系统疾病等。近年来对间质干细胞分化潜能及其应用研究较多,就间质干细胞神经分化潜能及其在神经系统疾病治疗中的应用研究进展做一综述。Mesenehymal stem cells have the pluripotency, they are so many souree, but they are most coming from marrow. Mesenehymal stem cells express many markers of the surface, however, no special one has been found until now. In some suitable condition, racsonehymal stem cells can differentiate to neuron. So they are the ideal .seeds of molecular engineering.They can be used to treat the disease of hematonosis, lymphoma, and some immunological disoases and some nervous system diseases. These years some studies are carried on the pluripotency and the application of the mesenehymnal stem cells. This paper reviews the current reports regarding the pluripoteney and the application of the mesenchumal stem cells in the neural system.

关 键 词：间质干细胞 分化 多能性 应用 

分 类 号：R741.05[医药卫生—神经病学与精神病学]