山东泰莱地区胃恶性肿瘤发生与ABO血型的相关性研究  

Study on the correlativity of ABO blood type of the patients from the Tai-Lai regions of Shandong province with their stomach neoplasms etiology

作　　者：李大鹏[1] 靳丽[1] 刘文清[1] 任红[1] 康俊升[1] 李静[2] 王锦庆[1] 

机构地区：[1]88医院检验科 [2]72253部队门诊部

出　　处：《实用医药杂志》2008年第3期344-345,共2页Practical Journal of Medicine & Pharmacy

摘　　要：目的研究胃恶性肿瘤发生与ABO血型抗原分布关系。方法选择山东泰安及莱芜地区胃恶性肿瘤患者686例,采用血型群体遗传学及血型血清学方法,进行ABO血型表现型及基因频率分布调查统计。结果发生胃恶性肿瘤的ABO血型抗原分布与对照组存在显著性差异(P<0.05)。结论提示发生胃恶性肿瘤与患者ABO血型间有显著相关性关系,血型因素是重要的胃恶性肿瘤易感因素。Objective To study the relativity between etiology of stomach carcinoma and ABO blood type antigen distribution. Methods ABO phenotype and their gene frequency distribution were investigated in 686 patients from the center south region of Shandong province by using blood type population genetics and serology assay. Results The significant difference in ABO blood type antigen distribution was found between the patients with carcinoma of stomach and the controls （P〈0.05）,i. e. there was some significant correlativity between the probability suffering from the disease and ABO blood type. Conclusion There is significant correlativity between etiology of stomach carcinoma and ABO blood type, so blood type is an susceptible factor that leads to carcinoma of stomach.

关 键 词：胃恶性肿瘤 ABO血型 血型抗原 

分 类 号：R735.2[医药卫生—肿瘤]