甲状腺微小癌的临床及病理分析  

Clinicopathologic Analysis of Thyroid Microcarcinoma

作　　者：王化修[1] 陈小红[1] 肖小芹[1] 

机构地区：[1]邵阳医学高等专科学校病理教研室,湖南邵阳422000

出　　处：《实用临床医学（江西）》2008年第2期1-2,6,共3页Practical Clinical Medicine

基　　金：湖南省科技计划项目(2007FJ3092);湖南省青年骨干教师培养基金(湘教通[2007]256号);湖南省卫生厅科研基金(B2005-122);湖南省教育厅科研基金(06C076)联合资助

摘　　要：目的探讨甲状腺微小癌（thyroid microcarcinoma,TMC）的临床及组织病理学特征。方法回顾性分析1988～2006年间收治的63例TMC的临床、病理和随访资料。结果男5例,女58例。发病年龄17～60岁,中位年龄37岁。巨检：55例见质硬而致密的灰白色瘢痕组织样区域;7例见深红色牛肉样实变区;1例为囊性结节。组织学类型：乳头状癌61例,滤泡癌2例。单发60例,多发3例。伴颈淋巴结转移2例。63例中随访48例（76.1%）,平均随访（125.6±26.9）月,术后随访10年者29例,10年生存率为96.6%（28/29）。结论甲状腺微小癌绝大多数并存于甲状腺良性疾病中,女性多发,以乳头状癌多见,淋巴结转移率低,预后好。Objective To investigate the clinical and pathological characteristics of thyroid microcarcinoma（TMC）. Methods The clinicopathologic and follow-up information of 63 cases TMC treated from 1988 to 2006 in our hosipital were analyzed retrospectively. Results The male and female patients were 5 and 58 respectively. The onset age ranged from 17 to 60 years old with a median of 37 years. Macroscopically,55 cases appeared as hard and rray scar tissue,7 cases appeared as dark red consol region just like beef meat, 1 case appeared as cystic nodules. Sixty-one of them were papillary thyroid carcinoma and 2 were follicular thyroid carcinoma. There were 60 cases with single tumor and 3 cases with multiple ones. Lymph nodes of neck metastasis were dem- onstrated in 2 cases. Forty eight patients（76. 1%）were followed up for mean time of（125.6± 26.9）months. Twenty-nine patients were followed up for 10 years,showing 96.6%（28/29） of 10-years survival rate. Conclusion Mostly,TMC coexists in patients with ben, ign thyroid disease. It＇s more common in female than in male. The papillary thyroid carcinoma is the most common histological type. There are lower lymph-node metastasis rate and a better prognosis.

关 键 词：甲状腺肿瘤 微小癌 临床病理 

分 类 号：R736.1[医药卫生—肿瘤]