急性脑血管病并发多器官功能衰竭患者腺垂体分泌功能研究  

FUNCTIONAL STUDY OF ADENOHYPOPHYSIS IN ACUTE CEREBROVASCULAR DISEASE

作　　者：李义召[1] 郭洪志[1] 王世华[1] 孙琳[1] 刘爱芬[1] 苏继新 迟兆福[1] 韩丹春[1] 王蕾[2] 

机构地区：[1]山东医科大学附属医院,250012 [2]济南铁路中心医院

出　　处：《中国现代医学杂志》1997年第9期1-3,共3页China Journal of Modern Medicine

摘　　要：对167例急性脑血管病（ACVD）患者血清泌乳素（PRI）、生长激素（GH）促黄体生成素（LH）、促滤泡成熟激素（FSH）、促甲状腺素（TSH）及血浆促肾上腺皮质激素（ACTH）水平进行了动态观察。结果发现：ACVD患者PRL、GH、ACTH、TSH、LH、FSH水平均显著高于对照组；ACVD并发多据官功能衰竭（MOF）患者PRL、GH、FSH水平显著高于ACVD疾病各组；随ACVD病程不同，6种激素水平也相应改变，1周时水平最高．2周后逐渐恢复；ACYD并MOF重型患者（MOF积分＞4分）PRL、GH水平显著高于轻型患者（MOF积分≤4分）。结果提示PRL、GH可能参与了ACVD并MOF的病理生理过程。The concentrations of serum PRL, GH, TSH, LH, FSH, and plasma ACTH were measured by radioim-munoassay in 167 acute cerebrovascular disease (ACVD) patients and the results were compared with those in age-matched control groups. The results show that the levels of PRL, GH, ACTH, LH, FSH, and TSH in the experi-mental group were significantly higher than those in the control group, and the levels of PRL, GH, and FSH in pa-tients with ACVD accompanied with MOF were higher than in patients with only ACVD. The abnormal parameters tended to recover after the clinical symptoms improved. The PRL and GH levels tended to correlate with the degree of severity of ACVD accompanied by MOF. This suggests that PRL and GF are involved in the pathophysiological process of ACVD accompanied by MOF, and its mechanism awaits further study.

关 键 词：急性 多器官功能衰竭 腺垂体 脑血管疾病 

分 类 号：R743.06[医药卫生—神经病学与精神病学] R59[医药卫生—临床医学]