原发性胆囊癌96例回顾性分析  

A retrospetive analysis on 96 primary gallbladder carcinoma cases

作　　者：亚森江·阿布都热依木[1] 李俊 栾梅香[1] 

机构地区：[1]新疆医科大学第一附属医院普外一科,乌鲁木齐830054

出　　处：《中华普通外科杂志》2008年第3期212-215,共4页Chinese Journal of General Surgery

摘　　要：目的探讨原发性胆囊癌的不同治疗方式、不同病理分期及分化程度对预后的影响。方法对1994年12月至2003年12月间连续收治的96例原发性胆囊癌病例的临床病理特点、不同的治疗方式及其随访结果进行生存分析。结果96例中手术治疗61例，非手术治疗及放弃治疗者35例。获得随访77例（80％）。NevinⅠ-Ⅲ期患者的预后明显好于Nevin Ⅳ—Ⅴ期患者。R0及R1切除术的3年生存率分别为80％及20％，R2切除术患者平均生存期为5．2个月，未行切除的患者平均生存期为2．5个月。结论早期诊断、民手术是胆囊癌患者长期存活的关键，病理分期对胆囊癌的预后有重要影响。Objective To evaluate the operative modality, pathological grade and tumor differentiation of patients with primary carcinoma of the gallbladder in their relations with prognosis. Methods The clinical and follow-up data of 96 consecutive patients with primary carcinoma of the gallbladder were retrospectively analyzed. Results Seventy-seven cases were followed-up. Patients treated by Ro resection had a 3 year survival rate of 80%, while it was only 20% for R1 resection group. Patients with R0 resection had an average survival of 5.2 months, 96% patients that treated conservatively died within the first 6 month with a mean survival time of 2.5 months. Conclusions The postoperative prognosis is mainly determined by the pathological stage of the tumor and the surgical margins. Early diagnosis and Ro resection are essential for a long survival time for patients with gallbladder carcinoma.

关 键 词：胆囊肿瘤 外科手术 病理学 预后 

分 类 号：R735.8[医药卫生—肿瘤] R576[医药卫生—临床医学]