拉莫三嗪治疗儿童癫痫合并注意障碍伴多动的自身对照研究  

Effectiveness of Lamotrigine on children with epilepsy complicated by attention-deficit hyperactivity disorder

作　　者：刘玉玺[1] 刘聪喜[1] 徐家立[2] 崔爱勤[2] 张守文[2] 

机构地区：[1]山西医科大学癫痫研究所,山西省太原市030053 [2]山西医科大学第三医院,山西省太原市030053

出　　处：《国际神经病学神经外科学杂志》2008年第1期6-8,共3页Journal of International Neurology and Neurosurgery

摘　　要：目的探讨拉莫三嗪对儿童癫痫合并注意障碍伴多动的治疗效果。方法对拉莫三嗪（LTG）治疗癫痫合并注意障碍伴多动（ADHD）的患儿进行开放性自身对照临床试验，治疗期为1～2年。结果ADHD症状好转者9例，有效率为75％；癫痫发作频度减少≥50％，10例（83％），EEG好转率为75％。结论LTG治疗儿童癫痫合并ADHD是有效的。Objective To study the effectiveness of Lamotrigine （LTG） on children with epilepsy complicated by attention-deficit hyperactivity disorder （ADHD）. Methods An open auto-controlled clinical trial of LTG for the treatment of epilepsy complicated by ADHD was performed in 12 children. The patients were treated and followed up for 1-2 years. Results Improvement of symptoms of ADHD was found in 9 patients （75%）. Ten patients （83%） showed seizure decrease ≥50%. EEG records were improved in 9 patients （75%）. Condusions LTG treatment may be effective for epilepsy complicated by ADHD in children.

关 键 词：癫痫 注意障碍伴多动 拉莫三嗪 

分 类 号：R742.1[医药卫生—神经病学与精神病学] R644[医药卫生—临床医学]