胆胰管活检、刷检及脱落细胞检查对胆胰疾病的诊断价值  

DIAGNOSIS OF CHOLANGIO PANCREATIC DISEASES BY ENDOSCOPIC BILIARY AND PANCREATIC BIOPSY, BRUSH CYTOLOGY AND SUCTION CYTOLOGY

作　　者：任旭[1] 吴芳莲[1] 张国梁[1] 徐秀芬[1] 杜明[1] 

机构地区：[1]黑龙江省医院消化内科

出　　处：《中华消化内镜杂志》1997年第4期211-214,共4页Chinese Journal of Digestive Endoscopy

基　　金：黑龙江省科委九五攻关项目

摘　　要：为探讨经内镜组织学诊断法对胆胰疾病的诊断价值，对胆胰管狭窄或中断者在ＥＲＣＰ时做胆胰管活检、刷检及脱落细胞检查。胆管癌２３例，胰腺癌１８例，胆管炎性狭窄４例，慢性胰腺炎５例，均经手术或随访证实诊断。胆管活检２３例，胰管活检１５例，胆管刷检２３例，胰管刷检１２例，胆汁脱落细胞检查１３例，胰液脱落细胞检查５例。恶性疾病中胆、胰管活检的敏感性分别为４７．１％与４５．５％，胆、胰管刷检的敏感性分别为６８．８％与５０．０％，胆汁与胰液脱落细胞检查敏感性分别为２３．１％与４０．０％，特异性均为１００％。结果显示经内镜胆胰管活检、刷检与脱落细胞检查安全，以刷检敏感性最高，三种方法联合应用能进一步提高其敏感性。In order to investigate the value of histologic diagnosis for cholangio pancreatic diseases, biopsy, brush cytology and suction cytology were attempted at ERCP in 50 patients with stricture or obstruction of cholangio pancreatic duct, of which 23 being illed with cholangiocarcinomas, 18 pancrea tic cancers, 4 benign biliary stenosis and 5 chronic pancreatitis. The diagnosis was supported by operative specimen and/or imaging evidence (BUS, CT,etc).With malignancy, positive findings by biliary and pancreatic biopsies were 47 1% and 45 5% respectively. Those by brush cytology were 68 8% and 50%, while by suction cytology lowered to 23 1% and 40 0% accordingly. It is assumed that endoscopic bilio panereatic biopsies, brush and suction cytology are secure with relatively high diagnostic value.

关 键 词：活检 刷检 胆疾病 胰腺疾病 脱落细胞检查 

分 类 号：R575.604[医药卫生—消化系统] R576.04[医药卫生—内科学]