CT引导在线校正分次放疗间误差的研究进展  

Adrances in research of CT imaging guided online correction of interfractional patient variation

作　　者：王立英[1] 李宝生[1] 

机构地区：[1]山东省肿瘤医院放疗科,山东济南250117

出　　处：《中华肿瘤防治杂志》2008年第4期311-313,共3页Chinese Journal of Cancer Prevention and Treatment

基　　金：国家自然科学基金(30670617)

摘　　要：分次放疗间误差是影响患者放疗疗效的主要因素,在分次放疗过程中,根据肿瘤患者及其器官放疗过程中随时间变化的频率不同,可采用不同的CT扫描安排,评价分次放疗间的位置误差。将放疗当日图像与初始计划时图像进行配准,找出不同轴线上的位移矢量,通过移床调整患者的位置等在线摆位或通过调整多叶光栅的形状、形变剂量强度等在线调整放疗计划的方法校正。为兼顾效率和效能,可适当减少靶区勾画层数,并改进图像获取方法。Interfractional patient variation is the main factor affecting the results of radiotherapy. During fractional radiotherapy, different CT scan protocols can be applied to evaluate the anatomical variations according to patient/organ variation frequency. The three dimensional variation vectors can be found after registering the pre-treatment imaging every day and planning imaging. Then the variation can be partly corrected by online translating treatment couch or modulating radiotherapy planning, for example, adjusting multi-leaf collimator and deforming dose intensity. To give attention to workload and efficiency, defining less contours and improving imaging acquisition may be applicable.

关 键 词：放射剂量分次 体层摄影术 螺旋计算机 综述文献 

分 类 号：R730.5[医药卫生—肿瘤]