西酞普兰与文拉法辛治疗抑郁症的对照与研究  

Comparison of efficacy and safety between citalopram and venlafaxine in the treatment of depression

作　　者：谭伟[1] 龚飞中[1] 王艺[1] 魏庆平[1] 许晓英[1] 

机构地区：[1]四川省自贡市第五人民医院自井分院,四川自贡643000

出　　处：《海南医学》2008年第4期16-16,35,共2页Hainan Medical Journal

摘　　要：目的比较西酞普兰与文拉法辛治疗抑郁症的疗效及不良反应。方法将62例抑郁症患者随机分为两组,分别给予西酞普兰与文拉法辛治疗,疗程6周。用汉密尔顿抑郁量表(HAMD)及汉密尔顿焦虑量表(HAMA)在治疗前及治疗1、2、4、6周评定疗效,用副反应量表(TESS)评定不良反应。结果两组总体疗效相当,西酞普兰起效较快.两组不良反应均较轻,安全性好。结论西酞普兰与文拉法辛均是治疗抑郁症有效而安全的药物。Objective To compare clinical efficacy and The side effects between citalopram and venlafaxine in the treatment of depression. Methods Sixty two patients with depression were treated randomly with citalopram or venlafaxine for six weeks, and measured with Hamilton depressive scale （HAMD）, Hamilton anxiety scale （HAMA） and treatment emergent symptom scale （TESS） before treatment and 1、2、4、6 weeks after treatment. Results The both drugs were similar in efficacy. The side effects of both were less. Conclusions Citalopram and venlafaxine are equally effective and safe in treating depression.

关 键 词：西酞普兰 文拉法辛 抑郁症 

分 类 号：R749.4[医药卫生—神经病学与精神病学]