Synthesis and DNA cleavage activity of diiron(Ⅲ) complex bearing pyrene group  

作　　者：Xiao Qiang Chen Jing Yun Wang Tong Yan Zhang Li Zhu Zhang Xiao Jun Peng 

机构地区：[1]State Key Laboratory of Fine Chemicals. Dalian University of Technoloev. Dalian 116012. China [2]Department of Bioscience and Biotechnology, Dalian University of Technology, Dalian 116023, China

出　　处：《Chinese Chemical Letters》2008年第3期342-344,共3页中国化学快报（英文版）

摘　　要：As DNA cleavage agent, a new diiron（Ⅲ） complex （Fe2Lb）, in which a DNA-intercalator （pyrene） is covalently linked to a diferric moiety, has been synthesized and characterized. The DNA-binding property and DNA cleavage activity of the complex have also been investigated.As DNA cleavage agent, a new diiron（Ⅲ） complex （Fe2Lb）, in which a DNA-intercalator （pyrene） is covalently linked to a diferric moiety, has been synthesized and characterized. The DNA-binding property and DNA cleavage activity of the complex have also been investigated.

关 键 词：Diiron（Ⅲ） complex INTERCALATOR PYRENE DNA cleavage 

分 类 号：O6[理学—化学]