术中细胞学检查对乳腺癌前哨淋巴结诊断应用价值的研究  

Research on value of using cytopathology detection to diagnose sentinel lymph node during operation of breast cancer

作　　者：王爱兰[1] 刘敏[1] 陆作为[1] 宋冬[1] 左文述[2] 王永胜[2] 宋现让[1] 

机构地区：[1]山东省肿瘤医院检验科,山东济南250117 [2]山东省肿瘤医院乳腺外科,山东济南250117

出　　处：《中华肿瘤防治杂志》2008年第6期463-464,479,共3页Chinese Journal of Cancer Prevention and Treatment

摘　　要：目的:探讨术中细胞学检查对乳腺癌前哨淋巴结(SLN)诊断的价值。方法:对149例乳腺癌手术患者同时进行SLN术中细胞学与快速病理检查,与常规病理进行对比分析。结果:SLN术中细胞学检查诊断的敏感性、特异性和总准确率分别为86.2%、99.3%和96.7%;术中快速病理学检查的敏感性、特异性和总准确率分别为98.5%、100.0%和99.07%。两者差异无统计学意义,P>0.05。结论:术中细胞学检查可以作为快速病理的补充或替代手段用于乳腺癌SLN的诊断,正确取材和制片是提高诊断准确率的关键。OBJECTIVE： To evaluate the value of cytopathology detection in diagnosis of sentinel lymph node during the operation of breast cancer. METHODS：During the operation of 149 cases of breast cancer, stamping slides and quick frozen tissue samples of sentinel lymph node were simultaneously examined, and the results were compared with conventional pathological diagnosis. RESULTS： The sensitivity, specificity and overall accuracy rate of cytopathology examination were 86.2%, 99.3% and 96.7%, respectively. In fast pathology diagnosis, they were 98. 5% ,100. 0% and 99. 7% respectively. There were no significant difference between the two methods, P〉0. 05. CONCLUSIONS：Cytopathology examination can be used as a complementary or altered method in diagnosis of sentinel lymph node in breast carcinoma operation. Sampling correctly and preparation of slides is the key in cytopathology diagnosis.

关 键 词：乳腺肿瘤 细胞学技术 前哨淋巴结活组织检查 

分 类 号：R737.9[医药卫生—肿瘤]