15例原发性鼻腔鼻窦非霍奇金淋巴瘤临床分析  

Clinical analysis of primary nasal non-Hodgkin's lymphoma

作　　者：周安梁 安云芳[2] 赵长青[3] 

机构地区：[1]山西古交矿区总医院耳鼻咽喉科,太原030200 [2]山西医科大学第二临床医学院耳鼻咽喉科,太原030001 [3]同济大学附属东方医院耳鼻咽喉科

出　　处：《山西医科大学学报》2008年第3期272-275,共4页Journal of Shanxi Medical University

摘　　要：目的探讨原发性鼻腔鼻窦非霍奇金淋巴瘤的病理特征和临床特点。方法对15例鼻腔鼻窦非霍奇金淋巴瘤住院患者的临床资料进行回顾性分析,分别从病理、临床表现、误诊情况、治疗方法、生存情况等方面进行总结分析,采用小样本Kaplan-Meier统计生存率。结果15例患者经治疗,完全缓解11例,部分缓解4例,病人随访时间为17-72个月。8例病人被误诊,误诊率高(53%)。5年生存率为52.1%。结论鼻腔鼻窦淋巴瘤分为T、B和NK/T细胞淋巴瘤三种病理亚型;该病临床表现缺乏特异性,容易误诊。及时进行活组织病理学检查,是确诊的关键。Objective To discuss the clinical characteristics and pathological features of primary nasal non-Hodgkin＇s lymphoma.Methods The pathological change,clinical manifestations,misdiagnosis,treatment and survival rate of 15 patients suffering from primary nasal non-Hodgkin lymphoma were analyzed retrospectively.The clinical data was analyzed by Kaplan-Meier survival curve.Results Of 15 cases,11 had complete remission,and 4 had partial remission.The patients were followed-up for 17-72 months.Eight cases were misdiagnosed,and the rate of misdiagnosis was 53%.Five-year survival rate was 52.1%.Conclusion Primary nasal non-Hodgkin lymphoma is classified into 3 pathological types：T,B,and NK/T-cell lymphoma.The patients have no special clinical manifestations.It is easily misdiagnosed.Early biopsy may be a key for diagnosis.

关 键 词：淋巴瘤 非霍奇金 鼻肿瘤 诊断 放疗 化疗 

分 类 号：R739.62[医药卫生—肿瘤]