波利维联合低分子肝素治疗短暂性脑缺血发作疗效观察  

The curative effect observation on the treatment of transient ischemic attack(TIA) with the Polivy combined with the low molecular weight heparin

作　　者：张全新[1] 吴霞[1] 周菁[1] 

机构地区：[1]新汶矿业集团莱芜中心医院,山东莱芜271103

出　　处：《泰山医学院学报》2007年第11期874-876,共3页Journal of Taishan Medical College

摘　　要：目的探讨波利维联合低分子肝素治疗短暂性脑缺血发作(TIA)的疗效。方法160例患者随机分为治疗组(82例)和对照组(78例),治疗组应用波立维75 mg qd×30 d、低分子肝素钠5000 u ih q12h×10 d;对照组仅用阿斯匹林、脱水剂、他汀等。结果治疗组全血黏度、纤维蛋白原(Fg)、血栓前体蛋白(TpP)、CRP、血小板聚集率、血小板计数及TIA发作停止例数(P<0.05)等方面较对照组差异有统计学意义。结论两种药物联合治疗有协同作用且安全有效,可有效控制TIA向脑梗死转化。Objective： To discuss the curative effect observation on the treatment of transient ischemic attack （TIA） with the Polivy combined with the low molecular weight heparin. Method： One hundred and sixty patients were randomly divided into the treatment group （82 examples） treated with Polivy 75 mg qd×30 day, low molecular weight heparin sodium 5000 u ih ql2h ×10 day and the control group （78 examples） with the aspirin, osmotic diuretics, tatin only. Results： There was significant difference in blood viscosity, fibrinogen（ Fg）, thrombus precursor protein （TpP）, CLIP, platelet aggregation rate, platelet count and number of no sudden occurrence of TIA （ P 〈 0.05） in the treatment group. Conclusion ： The treatment of transient ischemic attack （TIA） with the Polivy combined with the low molecular weight heparin is safe and effective, which can also control TIA transformation into cerebral infarction.

关 键 词：波利维 低分子肝素 短暂性脑缺血发作 

分 类 号：R743.31[医药卫生—神经病学与精神病学]