糖精实验测定正常青年人鼻腔黏液纤毛传输时间  

Saccharin test for nasal mucociliary transport time in the normal young people

作　　者：王奎吉[1] 张罗[1,2] 韩德民[1,2] 宋晓红[1] 羡慕[1] 

机构地区：[1]首都医科大学附属北京同仁医院耳鼻咽喉头颈外科,耳鼻咽喉头颈科学教育部重点实验室(首都医科大学) [2]北京市耳鼻咽喉科研究所,北京100005

出　　处：《中国耳鼻咽喉头颈外科》2008年第3期142-144,共3页Chinese Archives of Otolaryngology-Head and Neck Surgery

基　　金：国家重点基础研究发展计划(973前期;2007CB516706);国家"十一五"科技支撑计划(2007BAI18B15)联合资助

摘　　要：目的应用糖精实验法检测正常青年人鼻腔黏液纤毛传输时间(mucociliary transport time,MTT)正常值。方法应用糖精实验法测量52例健康青年鼻腔MTT,观察性别和鼻腔侧别对MTT的影响。结果52例受试者均完成糖精实验,MTT正常值为(504±141)秒,男性与女性MTT均值差异无统计学意义,双侧鼻腔MTT均值差异无统计学意义。结论糖精实验是评估鼻腔黏液纤毛传输功能的较好方法,性别和鼻腔侧别对MTT无显著影响。OBJECTIVE To explore the normal value of the nasal mucociliary transport time （MTT） measured with the saccharin test. METHODS Fifty-two healthy young volunteers participated in this study. MTT was investigated with the saccharin test. The normal value of MTT was evaluated after statistical analysis with SPSS software, and the effect of sex and nasal cavity side on MTT was also evaluated. RESULTS All subjects completed the saccharin test successfully, and the normal value of MTT was （504±141） seconds. Sex and nasal cavity side difference showed no effect on MTT. CONCLUSION The saccharin test appears to be an useful method in evaluating the mucociliary transport. Sex and nasal cavity side difference may be not the factors affecting the mucociliary transport.

关 键 词：黏液纤毛清除 鼻腔 糖精 

分 类 号：R765[医药卫生—耳鼻咽喉科]