输血与肿瘤复发的相关性  

The correlation between blood transfusion and tumor recurrence

作　　者：范垂姝[1] 金海甲[1] 魏微[1] 张丽英[1] 刘飞[1] 

机构地区：[1]吉化集团公司总医院一院,吉林吉林132021

出　　处：《现代肿瘤医学》2008年第4期684-685,共2页Journal of Modern Oncology

摘　　要：输血是临床应用广泛的治疗恶性肿瘤的手段,但输血引起的术后肿瘤复发等后果往往被人们所忽视,其作用是由血液成分中的一种或多种免疫抑制成分所引起的。近年研究表明,输血对受体的免疫调节起着双重作用,一方面可使移植成活时间延长,另一方面也可能引起肿瘤复发。有关输血对肿瘤患者预后影响的回顾性临床研究已相继开展;动物实验也在分子生物学水平取得了机制研究的新突破。在积极开展前瞻性研究的同时,应严格输血指征,提倡自体输血或成分输血,以减少输血对肿瘤患者预后的不良影响。Blood transfusion has been widely used as a therapy for cancer patients bat it may cause postoperative recurrence. The recent studies showed that blood transfusion can expand the time of transplanting success ;in another, tumor reccurence may be caused . The retrospective clinical analysis on prognosis of blood transfusion has been studied. Animal experiments on the level of molecalar biology also have been done . We should make the indication of blood transfusion strictly, encourage autotransfusion or component transfusion in order to reduce the in fluence of blood transfusion to cancer patients .

关 键 词：输血 免疫抑制 肿瘤复发 

分 类 号：R730.3[医药卫生—肿瘤]