乳腺大汗腺癌临床病理分析及鉴别诊断  

Clinicopathologic analysis and differential diagnosis of apocrine carcinoma

作　　者：肖萍[1] 薛玲[1] 彭建军[2] 吴惠茜[1] 车丽洪[1] 

机构地区：[1]中山大学附属第一医院病理科,广州市510080 [2]中山大学附属第一医院外科,广州市510080

出　　处：《实用诊断与治疗杂志》2008年第4期272-273,276,I0001,共4页Journal of Practical Diagnosis and Therapy

摘　　要：目的:探讨乳腺大汗腺癌的临床病理特征、诊断及鉴别诊断。方法:对相关病例进行病理组织学和免疫组织化学观察并复习文献。结果:乳腺大汗腺癌具有特征性的病理改变。几乎所有肿瘤细胞具有大汗腺分化。表现为肿瘤细胞胞质丰富,部分细胞胞质强嗜酸性,部分细胞胞质内有数量不等的细小空泡,或呈泡沫状。结论:乳腺大汗腺癌是一种罕见的乳腺癌,诊断主要依赖于形态学,需要与伴有大汗腺化生的其他乳腺病变相鉴别。Objective To explore the clinicopathologic features of apocrine carcinoma of the breast, and its diagnosis and differential diagnosis. Methods A specimen from 1 case of apocrine carcinoma of the breast was observed with histopathology and immunohistochemistry method, and the literatures were reviewed. Results Apocrine carcinoma of the breast had special pathological changes. The tumor was almost completely composed of apocrine cells; cells with abundant cytoplasm may be eosinophillc and vacuolated. Conclusion Apocrine carcinoma of the breast is a rare kind of breast tumors. Its diagnosis mainly relies to morphology. It should be distinguished with other diseases of breast with apocrine metaplasia.

关 键 词：乳腺癌 大汗腺癌 大汗腺化生 鉴别诊断 

分 类 号：R737.9[医药卫生—肿瘤]