CLINICAL REPORT ON MULTI-CENTER RANDOMIZED CONTROLLED TRIAL OF TREATMENT OF MIGRAINE BY ELECTRO-ACUPUNCTURE AT QI■X■(丘墟GB40)  

电针丘墟穴治疗偏头痛多中心随机对照研究(英文)

作　　者：贾春生[1] 马小顺[1] 石晶[2] 王耀民[3] 李永方[4] 袁军[3] 李梅[3] 郑利星[4] 张祥建[5] 王少锦[1] 高建英[1] 李晓峰[4] 霍永利[3] 

机构地区：[1]河北医科大学中医学院 [2]河北医科大学基础课部 [3]河北医科大学附属中医院 [4]白求恩国际和平医院 [5]河北医科大学附属第二医院

出　　处：《World Journal of Acupuncture-Moxibustion》2008年第1期1-9,共9页世界针灸杂志（英文版）

基　　金：国家中医药管理局临床研究课题,项目编号:03XDLZ17~~

摘　　要：Objective To observe the therapeutic effect of electro acupuncture at QIǖXǖ（丘墟GB40） for treating migraine and provide clinical study for Acupoints Dictionary of People＇s Republic of China. Methods Multi-center （3 First-Class hospitals） study was adopted, and the involved 3 hospitals did clinical observation according to the requirements of the project. The methods are as follows. All cases were randomized into treatment group and control group according to their sequence. QIǖXǖ（丘墟GB40） was selected in treatment group, while Tiānshū （天枢 ST25） was selected in control group. Both groups were performed electro acupuncture, and syndromes indexes of migraine and 5-HT were observed before and after treatment. All data were analyzed by statistic software SPSS11.5. Results There was significant difference of VAS margin between two groups in each center and the combined center （u= -3. 362, P=0. 001 ）. There was significant difference of therapeutic effect of 4-week treatment between two groups in each clinical center and the combined center. The therapeutic effect of 3-month treatment between two groups in No. 1 and No. 3 hospitals, showed significant difference, the treatment group was better; while that of No. 2 hospital had no obvious difference. The therapeutic effect of 6-month treatment between two groups in each center and the combined center had significant difference, the treatment group was better. Conclusion The therapy of electro acupuncture at QIǖXǖ（丘墟GB40） is effective for migraine.目的:观察电针丘墟穴治疗偏头痛的疗效,为《中华人民共和国针灸穴典》提供丘墟穴主治偏头痛的临床研究资料。方法:采用了多中心(3家三甲临床医院)同时按照任务书的要求分别进行临床观察,以天枢穴为对照组,按照就诊的先后顺序查随机数字表进行分组,治疗组和对照组均采用电针方法,观察治疗组和对照组治疗前后的偏头痛各项临床症状指标和5-羟色胺(5-HT)。将所得数据,用SPSS11.5统计软件进行统计学处理与分析。结果:3所医院合并的两组患者VAS差值差别有显著性(u=-3.362,P=0.001)。3个临床中心和合并的两组患者4周疗效差别均有显著性,治疗组的效果好。第一、第三临床中心和合并的两组患者3个月疗效差别均有显著性,治疗组的效果好。第二临床中心的两组患者3月疗效差别无显著性。3个临床中心和合并的两组患者6个月疗效差别有显著性,治疗组的效果好。结论:电针丘墟穴治疗偏头痛是一种有效的方法。

关 键 词：QIǖXǖ（丘墟GB40） Electro acupuncture Migraine Multi-center clinical observation 

分 类 号：R246[医药卫生—针灸推拿学]