小鼠肿瘤浸润淋巴细胞联合放疗对小鼠宫颈癌U_(14)的治疗作用  

Antitumor Effect of TIL Combined with Radiotherapy on Mouse Uterocervical Cancer U 14

作　　者：廖贵清[1,2] 毛祖彝[1,2] 徐平平[1,2] 

机构地区：[1]华西医科大学口腔医学院口腔颌面外科 [2]中山医科大学附属光华口腔医院

出　　处：《华西口腔医学杂志》1997年第3期258-259,共2页West China Journal of Stomatology

基　　金：卫生部科研基金

摘　　要：利用Ｒｏｓｅｎｂｅｒｇ实验室建立的肿瘤浸润淋巴细胞（ＴＩＬ）制备方法对小鼠宫颈癌ＴＩＬ进行分离培养，在建立小鼠宫颈癌Ｕ１４移植瘤的基础上，用ＴＩＬ联合局部放疗治疗，观察抗瘤作用。结果发现，小鼠ＴＩＬ及放疗对小鼠宫颈癌Ｕ１４均有较好的抑制生长作用，二者联合使用，其抑瘤作用更强，Ｅ／Ｏ值为１．１。提示，ＴＩＬ治疗与放疗存在相加关系。After yielding culturing mouse TIL from U 14 with Rosenberg's technique, the authors observed the antitumor effect of TIL combined with radiotherapy on established mouse transplanted tumor of uterocervical cancer U 14 . The results demonstrated TIL treatment or radiotherapy could inhibit the tumors growth. Combination showed a stronger inhibition and the E/O value was 1.1. It implied that an additive effect was gotten when conbining TIL with radiotherapy.

关 键 词：宫颈癌 放射疗法 肿瘤浸润 淋巴细胞 口腔肿瘤 

分 类 号：R737.330.5[医药卫生—肿瘤] R739.805[医药卫生—临床医学]