两种浓度氟保护漆在体外对人牙釉质光滑面、窝沟人工龋的影响  

Study on inhibitory effect of two fluor protectors with different concentrations on human enamel smooth surface and socket in vitro

作　　者：王金华[1] 林居红[1] 蒋琳[1] 杨刚[1] 张红梅[1] 

机构地区：[1]重庆医科大学附属口腔医院口腔预防科,重庆400015

出　　处：《重庆医科大学学报》2008年第3期337-340,共4页Journal of Chongqing Medical University

基　　金：重庆市科委科研基金资助(渝科发计字[2004]54号文件)。

摘　　要：目的:比较2种浓度氟保护漆在体外对人牙釉质光滑面、窝沟人工龋的影响。方法:将40个光滑面和40个窝沟无龋的牙釉质块分别随机分为4组,每组10个,5个用作实验,5个备用。实验组(0.5%氟保护漆、0.1%氟保护漆):牙釉质表面吹干后分别连续均匀涂布0.5%氟保护漆、0.1%氟保护漆2次,自然干燥后备用;阳性对照组(0.05%氟化钠):牙釉质块浸入0.05%氟化钠溶液中24h,取出干燥后备用;空白对照组(去离子水):牙釉质块浸入去离子水中24h,取出干燥后备用。然后将标本放置于人工致龋液中37℃恒温168h,从致龋液中取出,蒸馏水冲洗并吹干,高速金刚沙盘喷水条件下沿实验开窗区颊舌向将牙釉质块分为两半,一半用于偏光显微镜观测龋损深度,一半用于扫描电镜观察釉质表面脱矿情况。结果:0.5%氟保护漆组龋损深度最小;0.5%氟保护漆组与0.1%氟保护漆组之间有显著性差异(P<0.05)。结论:0.5%氟保护漆、0.1%氟保护漆均能够有效阻碍牙釉质人工龋坏的发展。0.5%氟保护漆抑制人工龋坏的效果明显好于0.1%氟保护漆。Objective：To observe and compare the inhibitory effect of two fluor protectors with different concentrations on man-made dental caries of human enamel smooth surface and socket in vitro. Methods：Forty smooth surfaces and forty sockets non-carious human enamels were divided into four groups randomly. Each group had ten samples,five samples were employed to experiment,and five samples were used as spare ones. For experiment group（0.5%fluor protector,0.1% fluor protector ）,the dental enamel surfaces were spreaded 0.5% fluor protector and 0.1% fluor protector twice in series respectively. For positive control group（0.05% NaF）,the dental enamels were dipped into 0.05% NaF for 24h,then taken out and dried.For blank control group（ deionized water） ,the dental enamels were immersed into deionized water for 24h, then taken out and dried. The specimens were taken out of when they had been immersed into man-made cariogenic fluid（37℃） for 168h,rinsed and dried, then they were divided into two halves by high speed corundum disk in spurting water;one half was used to observe depth of dental caries by polarization microscope,and the other half was employed to observe surface demineralization by scanning electron microscope. Results：The dental Caries depth of 0.5% fluor protector group was the smallest in four groups,and there were significant differences between 0.5% fluor protector group and 0.1% fluor protector group（P〈0.05）. Conclusion：Two fluor protectors with different concentrations are effective in decreasing the depth of man-made dental caries.But the caries resistance effect of 0.5% fluor protector is better than that of 0.1% fluor protector,s obviously.

关 键 词：氟保护漆 防龋 牙釉质 

分 类 号：R781.1[医药卫生—口腔医学]