杭州市2001-2006年无脊髓灰质炎阶段连续监测分析  

Acute Flaccid Paralysis Surveillance during Polio Free Phase from 2001-2006 in Hangzhou City

作　　者：黄利明[1] 许二萍[1] 高峰[2] 祝水芬[1] 杨洛贤[1] 朱冰[1] 张小平[1] 刘艳[1] 

机构地区：[1]杭州市疾病预防控制中心,浙江310006 [2]浙江大学医学院附属儿童医院

出　　处：《中国预防医学杂志》2008年第2期105-108,共4页Chinese Preventive Medicine

基　　金：杭州市卫生局(2005B098)

摘　　要：目的为保持急性弛缓性麻痹（AFP）病例监测系统高效运转和处于敏感状态，达到能够及时发现相关病例并采取相应措施，为维持无脊髓灰质炎状态提供可靠依据。方法根据各区、县（市）2001—2006年连续6年健康人群免疫水平监测及AFP病例监测系统的专报资料和杭州市组织的每年一次对AFP监测医院的专项漏报调查，进行系统评估。结果连续6年共有AFP病例146例，无脊灰确诊病例，AFP病例报告发病率在1．65／10万-3．09／10万之间，5岁以下发病占76．71％。格林巴利综合征（GBS）占大多数，达到30．82％。6年共漏报3例，漏报率为1．03％。共分离到脊髓灰质炎病毒（PV）13例，最后鉴定均为疫苗株。连续6年共调查1125名健康对象，脊灰Ⅰ、Ⅱ、Ⅲ型抗体阳性率分别为99．64％、98．76％、99．56％；健康人群免疫水平高。结论连续6年的AFP监测表明，杭州市的AFP病例监测系统处于敏感状态。健康人群脊髓灰质炎免疫水平较高。有利于维持无脊髓灰质炎状态。Objective To maintain the acute flaccid paralysis （AFP） surveillance in highly effective and sensitive condition and to provide rehable basis for maintaining the Poho Free Phase. Methods Data of population immunity level and continuous AFP surveillance in every Hangzhou district from 2001 to 2006, and investigations of missing reports of hospital-based AFP surveillance organized by Hangzhou CDC each year were evaluated. Results Altogether 146 AFP cases were reported, among which no poliomyelitis cases were found in the six years. The reported incidence rate of AFP cases was between 1.65/100 000 and 3.09/100 000, and dilldren under 5 years accounted for 76.71% of all cases. Most of the cases suffered from GuiUain-barre syndrome （GBS） （accounting for 30.82%） .The cumulation missing report rate was 1.03% for there were 3 missing report cases in the past 6 years. Polio viruses （PV） were separated from 13 eases, and were all appraised for vaccine virus. In 1 125 healthy persons the positive rates of polio Ⅰ, Ⅱ, Ⅲ antibodies were 99.64%, 98.76%, 99.56% respectively. Conclusion The AFP surveillance system of Hangzhou was in sensitive condition. The healthy population polio immunity level was high, which was advantageous to maintain the Polio Free Phase.

关 键 词：急性弛缓性麻痹 监测 漏报 

分 类 号：R181.8[医药卫生—流行病学]