X刀治疗颅内肿瘤23例  

Treatment X-knife for intracranial tumors-a comparative study

作　　者：张兴华[1] 赵朋[1] 和航[1] 张晓军[1] 

机构地区：[1]新疆医科大学第一附属医院,乌鲁木齐830054

出　　处：《医学信息（手术学分册）》2008年第2期99-101,共3页Medical Information Operations Sciences Fascicule

摘　　要：目的探讨颅内肿瘤立体定向放射治疗(SRT)的方法与疗效。方法对比分析23例采用BRW分次、GTC低分次、多分次、高分次SRT治疗颅内肿瘤的治疗与随访资料。结果随访(23.31±13.83)月,1年生存率85.0%,生存期23.31月,实际肿瘤控制率86.67%。结论SRT疗效确节,并发症低,以小病变和多分次尤佳,优于单次治疗。但是,SRT需严格掌握适应证,根据病变部位、体积、性质、一般情况及放疗史等选择治疗方式和剂量。Objective To study the methodology and effectiveness of sterotactic radiotherapy（SRT） for intractanial tumors. Methods The treatment and long - term follow - up data of 23 cases with intracranial tumors,which were treated by fractionated （BRW） radiotherapy, hypofrac - tionated （GTC） radiotherapy, muhifractionated （GTC） radiotherapy and hyperfractionated（GTC） radiotherapy respectively ,are analyzed comparatively. Results Patients were fol- lowed up for（23.31 ±13.83） months. A one - year survival of 85.0% ,a survival time of 23.31 months and an actuarial local tumor control of 86.67% were achieved. Conclusions Definite curative effects with low morbidity of fractionated sterotactic radiotherapy on intracranial tumors were verified. And it was much better in those with small lesions and highly fractionated stereotactic radiotherapy. For patients in the same condition, the effectiveness of stereotactic radiotherapy was superior to that of the same single highdose stereotactic radiosurgery. The indi cations of SRT should be managed both cautiously and strictly. The schedule and dose should be selected rationally according to the location, nature and volume of the tumor,the general conditions and radiotherapy,history of the patient.

关 键 词：立体定向放射治疗 X-刀 肿瘤 脑 颅底 

分 类 号：R739.41[医药卫生—肿瘤]