青岛市民与住青韩国人脂肪肝人群流行病学特点及高危因素  

Epidemiological features and high risk factors of Qingdao residents and Koreans living in Qingdao with fatty liver

作　　者：王仁萍[1] 唐晓燕[2] 马先福[1] 李堃[3] 张积华[1] 郑淑芳[1] 王宏涛[1] 马莉娜[1] 

机构地区：[1]青岛大学医学院附属医院健康体检中心,山东省青岛市266003 [2]青岛大学医学院附属医院放射介入科,山东省青岛市266003 [3]青岛大学医学院附属医院ICU,山东省青岛市266003

出　　处：《世界华人消化杂志》2008年第9期962-965,共4页World Chinese Journal of Digestology

摘　　要：目的:研究青岛市民与住青韩国人脂肪肝(fatty liver,FL)人群流行病学特点及高危因素.方法:运用流行病学调查方法调查青岛市民FL患者1031例(青岛组),住青韩国人FL患者1543例(韩国组),填写相关内容,包括个人一般资料、腹部彩超检查及生化指标,应用SPSS11.0软件进行t检验、x^2检验及回归分析。结果:青岛市FL患病率35.49%,住青韩国人FL患病率16.68%,两组比较差别具有显著性(x^2=507.91,P<0.01);青岛组FL患者体质量指数(BMI)大于韩国组,两组比较差别具有显著性(t=13.10,P<0.01);青岛组FL患者空腹血糖(GLU)、胆固醇(TC)高于韩国组,二者具有统计学意义(t=2.31,t=3.51,P<0.05);男性FL患者超重、肥胖及高空腹血糖青岛组高于韩国组,有统计学意义(x^2=35.68,x^2= 61.49,x^2=3.88,P<0.05);女性FL患者超重、肥胖及高甘油三酯(TG)青岛组高于韩国组,有统计学意义(x^2=29.70、x^2=12.35、x^2= 9.88,P<0.05);多因素Logistic回归分析,两组FL患者均与肥胖、高甘油三酯(TG)密切正相关,与年龄、超重、高胆固醇(TC)和空腹高GLU呈正相关.结论:青岛市民FL患病率远高于住青韩国人,两组FL与肥胖、高TG密切正相关,与年龄、超重、高TC和空腹高GLU呈正相关.AIM： To investigate the epidemiological features and high risk factors of Qingdao residents and Koreans living in Qingdao with fatty liver. METHODS： One thousand and thirty one Qingdao residents （group A） and 1543 Koreans living in Qingdao （group B） with fatty liver were studied with epidemiological method and the relateddata including patients＇ general data, results of abdominal ultrasonic inspection and biochemical indicators were collected and analyzed by t-test, chi-square test and regression analysis using SPSS11.0 software. RESULTS： The morbidity rates of fatty liver in Qingdao residents and Koreans were 35.49% and 16.68%, respectively （x^2 = 507.91, P 〈 0.01）. The body mass index, the levels of fasting blood glucose and cholesterol in group A were higher than those in group B （t = 13.10, P 〈 0.01; t = 2.31, P 〈 0.05; t = 3.51, P 〈 0.05）. The rates of overweight, obesity and high fasting blood glucose of males in group A were also higher than those in group B （x^2 = 35.68, x^2 = 61.49, x^2 = 3.88; all P 〈 0.05）. But for females, the rates of overweight, obesity and hyperglyceridemia in group A were higher than those in group B （x^2 = 29.70, x^2 = 12.35, x^2= 9.88; all P 〈 0.05）. Logistic regression analysis of multiple factors suggested that fatty liver had a close positive correlation with obesity and hyperglyceridemia, and had a positive correlation with age, overweight, hypercholesterolemia and high fasting blood glucose in both groups. CONCLUSION： In comparison with Koreans living in Qingdao, fatty liver occurrs more frequently in Qingdao residents. The incidence of fatty liver has a close positive correlation with obesity and hyperglyceridemia, and has a positive correlation with age, overweight, hypercholesterolemia and high fasting blood glucose both in Qingdao residents and in Koreans living in Qingdao.

关 键 词：脂肪肝 流行病学 患病率 高危因素 

分 类 号：R575.5[医药卫生—消化系统]