急性冠脉综合征伴发焦虑抑郁情绪患者生活质量的研究  

Quality of life in patients with acute coronary syndrome combined anxiety and depressive symptoms

作　　者：马文林[1] 徐颖[1] 李美婧[1] 刘光辉[1] 李觉[2] 高文根[3] 胡大一[3] 

机构地区：[1]上海同济大学附属同济医院心内科,上海200065 [2]同济大学医学院流行病学教研室 [3]北京市人民医院心脏中心

出　　处：《中国行为医学科学》2008年第4期318-319,共2页Chinese Journal of Behavioral Medical Science

摘　　要：目的研究急性冠脉综合征（acute coronary syndrome，ACS）患者伴随焦虑抑郁情绪时的生活质量（quality of life，QOL）。方法使用综合性医院情绪测量表（HADS）和健康状况调查问卷（SF-36）分别对688例ACS住院患者进行情绪测量及QOL评估。根据HADS评分结果，将入组的ACS患者分为焦虑组、抑郁组、焦虑抑郁组以及非焦虑非抑郁组。结果焦虑组、抑郁组、焦虑抑郁组及非焦虑抑郁组QOL评分依次为：生理机能（56．92±23．92）分；（52．91±32．24）分；（53．03±27．34）分；（62．51±27．15）分、生理职能（31．08±38．49）分；（34．97±40．44）分；（23．86±33．60）分；（45．40±43．57）分、躯体疼痛（55．14±23．86）分；（55．78±29．45）分；（49．39±24．51）分；（65．39±24．98）分、一般健康状况（40．16±20．20）分；（39．74±21．39）分；（35．22±19．66）分；（51．09±21．98）分、精力（53．52±18．39）分；（55．81±21．60）分；（48．02±21．48）分；（66．68±23．13）分、社会功能（62．04±26．78）分；（62．99±28．31）分；（54．13±27．58）分；（75．83±24．90）分、情感职能（42．33±43．12）分；（51．64±44．65）分；（30．00±37．85）分：（58．69±44．83）分、精神健康（65．39±18．62）分；（72．11±20．46）分；（58．01±20．29）分；（82．69±16．43）分，组间比较差异有显著性（P〈0．05）。结论ACS患者伴发焦虑抑郁情绪时QOL显著降低，以伴发焦虑抑郁双重障碍的ACS患者的QOL最低。Objective To assess the quality of life （QOL） in patients with acute coronary syndrome （ACS） combined depressive symptoms and（or） anxiety. Methodes Hospital anxiety depressive symptoms scales （HADS） and short-form-36 health survey （ SF-36, Chinese version） were completed by 688 hospitalized patients with ACS. Results According to HADS scores,the study population were divided into four groups：anxiety group, depressive symptoms group, depressive symptoms combined anxiety group, non-anxiety or depressive symptoms group. QOL of each group had statistical differences. The score of physical functioning：56.92 ± 23.92,52.91 ± 32.24,53.03 ± 27.34,62.51 ± 27. 15. The score of social functioning： 31.08 ± 38.49,34.97 ± 40.44,23.86 ± 33.60,45.40 ± 43.57. The score of bodily pain ：55.14 ± 23.86,55.78 ± 29.45,49.39 ± 24.51,65.39 ± 24.98. The score of general health：40.16 ± 20.20,39.74 ± 21.39,35.22 ± 19.66,51.09 ± 21.98. The score of vitality： 53.52 ± 18.39,55.81 ± 21.60,48.02 ± 21.48,66.68 ± 23.13. The score of role-physical ：62.04 ± 26.78,62.99 ± 28.31,54.13 ± 27.58,75.83 ± 24.90. The score of role-emotional 42.33 ± 43. 12,51.64 _± 44.65,30.00 ± 37.85,58.69 ± 44.83. The score of mental heahh ：65.39 ± 18.62,72.11 ± 20.46,58.01 ± 20.29,82.69 ± 16.43 （ P〈 0.05 ）. Conclusion For ACS patients,symptoms of anxiety and depressive symptoms were associated with significant worsening of QOL.

关 键 词：焦虑 抑郁 急性冠脉综合征 生活质量 

分 类 号：R749.2[医药卫生—神经病学与精神病学]