不可逆相转移法合成茶多酚砷配合物及光谱研究  

Synthesis of Tea-polyphenol Arsenic Complex by Irreversible Phase Transfer and Its Characterizations

作　　者：周文富[1] 何清松[1] 

机构地区：[1]三明学院化学与生物工程系,福建三明365004

出　　处：《精细化工》2008年第4期347-350,共4页Fine Chemicals

摘　　要：采用不可逆相转移法,于水溶液中,在n（茶多酚）∶n（三氧化二砷）=10∶1,反应温度50～60℃,反应时间6h的条件下合成了标题化合物茶多酚砷。配合物的FTIR为：3417.16,1694.69,1619.55,1617.71,1508.95,1449.35,1351.99,1206.39,1037.54 cm^-1。UV为：220 nm,3.700Abs;250 nm,1.100Abs;275 nm,1.800Abs。^1HNMR,：δ1.180,2.840,5.409,6.058,6.490～7.123。白鼠急性口服毒性实验证实,合成的茶多酚砷为低毒有机物。In aqueous solution, by means of irreversible phase transfer, tea-polyphenol and AS2O3 in molar ratio 10：1 reacted at 50 -60 ℃ for 6 h to afford the title complex. The product was characterized by FTIR： v = 3 417.16, 1 694.69, 1 619. 55,1 617.71,1 508.95,1 449. 35,1 351.99, 1 206.39, 1 037.54 cm^-1;UV： （220 nm,3.700Abs）, （250 nm, 1.100Abs）, （275 nm, 1.800Abs）;and ^1HNMR,8： 1. 180,2.840,5.409,6.058,6.490 -7. 123. Rat acute oral toxicity show that, the synthesized tea-polyphenol arsenic complex proved to be an organic matter of low toxicity.

关 键 词：茶多酚 砷配合物 结构表征 中药现代化技术 

分 类 号：O627.52[理学—有机化学]