Immunosuppressive terpenoids from Tripterygium wilfordii  

作　　者：Qian Shen ZhiYao Yoshihisa Takaishi Yan Wen Zhang Hong Quan Duan 

机构地区：[1]School of Pharmaceutical Sciences,Basic Medical Research Center of Tianjin,Tianjin Medical University,Tianjin 300070,China [2]Department of Immunology,Tianjin Medical University,Tianjin 300070,China [3]Faculty of Pharmaceutical Sciences,University of Tokashima,Tokushima 770-8505,Japan

出　　处：《Chinese Chemical Letters》2008年第4期453-456,共4页中国化学快报（英文版）

摘　　要：Two new terpenes,triptobenzene P（1）and wilforone（2）were isolated from Tripterygium wilfordii,as well as 10 known terpenes.Their structures were elucidated by spectroscopic methods.Compounds 2-4,8,10,and 11 showed significant immunosuppressive activities.Two new terpenes,triptobenzene P（1）and wilforone（2）were isolated from Tripterygium wilfordii,as well as 10 known terpenes.Their structures were elucidated by spectroscopic methods.Compounds 2-4,8,10,and 11 showed significant immunosuppressive activities.

关 键 词：Tripterygium wilfordii DITERPENE TRITERPENE Immunosuppressive activity 

分 类 号：R284[医药卫生—中药学] R282.71[医药卫生—中医学]