DITERPENE

作品数:96被引量:156H指数:6
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相关领域:理学医药卫生更多>>
相关作者:冯锋刘静涵王伟石青朱平更多>>
相关机构:中国药科大学中国医学科学院北京协和医学院兰州大学福建医科大学更多>>
相关期刊:《Chinese Herbal Medicines》《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》《Science China Chemistry》更多>>
相关基金:国家自然科学基金中国博士后科学基金中国科学院科研项目国家重点基础研究发展计划更多>>
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Study on the regulatory effect of liver X receptor in HEK293 cells by six main diterpene esters in Semen Euphorbiae
《TMR Modern Herbal Medicine》2024年第2期35-40,共6页Si-Yuan Ma Fan-Miao Kong Xiao-Tong Wei Jun-Li Zhang Hai-Ting Zhu Xin-Ning Zhang Yu-Feng Hu Ming-Rui Jiang Hui-Nan Wang Yi-Cen Xu Ying-Zi Wang 
supported by National Natural Science Foundation of China(Grant No.82074021).
Background:To study the effects of the main diterpene esters in Euphorbia factor L_(1),L_(2),L_(3),L_(7a),L_(7b)and L_(8)on the transcriptional activity and protein expression of liver X receptor(LXR).Methods:The effe...
关键词:Semen Euphorbiae diterpene esters HEK293 LXR dual luciferase reporter gene system 
Simple isocratic RP-UHPLC-MS methods for the determination of steviols and its glycosides:Quality control perspectives
《Food Bioscience》2023年第3期1999-2012,共14页Pawan Kumar Dinesh Kumar Vivek Yadav Sushil K.Maurya Rajiv K.Tonk Dinesh Kumar 
Stevia is well-known for its unique non-caloric intense sweetness and recognising as one of the most acceptable sweeteners.Therefore,quality control and metabolite profiling perspectives,two isocratic reverse-phase UP...
关键词:Stevia rebaudina Steviols Steviol glycosides Quality control Diterpene glycosides UHPLC-MS/MS 
Sustainable biosynthesis of valuable diterpenes in microbes
《Engineering Microbiology》2023年第1期65-79,共15页Yanbin Liu Xixian Chen Congqiang Zhang 
supported by the Agency for Science,Technology and Research(A∗STAR),Singapore:AME Young Individual Research Grant(YIRG)A2084c0064(Dr.Congqiang Zhang)and A1984c0040(Dr.Xixian Chen);A∗STAR Central Strategic Fund for the Singa-pore Integrative Biosystems and Engineering Research(SIBER)Program C211917009.
Diterpenes,or diterpenoids,are the most abundant and diverse subgroup of terpenoids,the largest family of sec-ondary metabolites.Most diterpenes possess broad biological activities including anti-inflammatory,antivira...
关键词:Diterpene/diterpenoid Secondary metabolites Synthetic biology Metabolic engineering BIOSYNTHESIS 
Forrestiacids C and D,unprecedented triterpene-diterpene adducts from Pseudotsuga forrestii
《Chinese Chemical Letters》2022年第9期4264-4268,共5页Peng-Jun Zhou Yi Zang Cong Li Lin Yuan Huaqiang Zeng Jia Li Jin-Feng Hu Juan Xiong 
supported by grants from the National Natural Science Foundation of China(Nos.21937002,81773599,21772025)。
Forrestiacids C(1)and D(2),a pair of C-25 epimeric triterpene–diterpene adducts were isolated from the needles and twigs of the vulnerable conifer Pseudotsuga forrestii.This unprecedented class of compounds might be ...
关键词:Forrestiacid Pseudotsuga forrestii PINACEAE Michael adduct Lipogenesis inhibitor 
Cathayanalactone G and other constituents from leaves and twigs of Callicarpa cathayana被引量:1
《Chinese Herbal Medicines》2022年第2期332-336,共5页Shuang Gong Bin Cheng Tiantian Sun Xiaoli Li Xinxin Liang Yuan Wang Xiaochang Dai Weilie Xiao 
financially supported by the Natural Science Foundation of China(No.21762048,81860615 and 81903541);Yunnan Applicative and BasicResearch Program(No.2018FY001);the grant of Yunnan Applicative and Basic Research Program(No.2018FA048);the Program for Changjiang Scholars and Innovative Research Team in University(No.IRT_17R94);Project of Innovative Research Team of Yunnan Province(No.202005AE160005);Yun Ling Scholar Project to Wei-e Xiao。
Objective:To study the chemical constituents from the leaves and twigs of Callicarpa cathayana.Methods:The chemical constituents were isolated and purified by column chromatography on silica gel,MCI gel CHP 20 P/P120,...
关键词:Callicarpa cathayana H.T.Chang cathayanalactone G FLAVONOIDS labdane diterpene TRITERPENOIDS 
Distinctive Cassane Diterpenoids Corroborated Biogenetic Evolutionary Process from Caesalpinia mimosoides with Anti-renal Fibrosis Activity被引量:2
《Chinese Journal of Chemistry》2022年第5期617-627,共11页Xinxin Zhang Yan Yin Yu Zhou Tianliang Zhu Miao Wang Huiyuan Gao 
The authors are grateful to the received financial support from the National Natural Science Foundation of China(No.31670359);the Liaoning Revitallzation Talents Program(No.XLYC 1905019);the Natural Science Foundation of Llaoning Province(No.201602691).
Eighteen diterpenoids were isolated from the seeds of Caesalpinia mimosoides,including four extremely infrequent cassane diterpenes,together with nine new and five known structures.Compounds 7 and 8 represent the firs...
关键词:Cassane diterpene Caesalpinia mimosoides Natural products Molecular evolution Biological activity 
Furanocembranoid from the Okinawan soft coral Sinularia sp.
《Natural Products and Bioprospecting》2022年第1期71-77,共7页Misaki Nagasaka Kazuki Tani Keisuke Nishikawa Riri Kinjo Takahiro Ishii 
One new furanocembranoid diterpene,11-hydroxy-Δ^(12(13))-pukalide(1),along with six known secondary metabolites,11-acetoxy-Δ^(12(13))-pukalide(2),13α-acetoxypukalide(3),pukalide(4),3α-methoxyfuranocembranoid(5),Δ...
关键词:Soft coral Sinularia sp. Furanocembranoid DITERPENE 
New acetogenin katsuurallene from Laurencia saitoi collected from Katsuura, Japan
《Natural Products and Bioprospecting》2022年第1期121-127,共7页Yu Minamida Hiroshi Matsuura Takahiro Ishii Miyu Miyagi Yuto Shinjo Kosuke Sato Takashi Kamada Yoshihiro Mihara Iwao Togashi Keisuke Sugimoto Tsuyoshi Abe Norio Kikuchi Minoru Suzuki 
supported by JSPS KAKENHI Grant Numbers 18K05799 and 21K14904.
We examined the chemical constitution of the red alga Laurencia saitoi Perestenko,collected from Katsuura,Boso Peninsula,Chiba Prefecture,Japan.This specimen produced a new polyhalogenated acetogenin,named katsuural-l...
关键词:LAURENCIA RHODOMELACEAE ACETOGENIN TRITERPENE DITERPENE Biological activity 
Au-Catalyzed 1,3-Acyloxy Migration/Cyclization Cascade:A Direct Strategy toward the Synthesis of Functionalized Abietane-Type Diterpenes
《CCS Chemistry》2021年第11期2795-2802,共8页Tian-Lu Zheng Si-Zhan Liu Chen-Yu Huo Jing Li Bo-Wen Wang Da-Ping Jin Fu Cheng Xiao-Ming Chen Xiao-Ming Zhang Xue-Tao Xu Shao-Hua Wang 
supported by the National Natural Science Foundation of China(nos.21472077 and 21772071);Department of Education of Guangdong Province(nos.2017KTSCX185,2017KSYS010,2016KCXTD005,and 2019KZDXM035).
A direct strategy toward the synthesis of functionalized abietane-type diterpenes and related polycyclic molecules was developed through an Au-catalyzed 1,3-acyloxy migration/cyclization/electrophilic aromatic substit...
关键词:polyene cyclization Au catalysis tandem reaction DITERPENE propargylic ester 
Clerodane-type Diterpene Glycosides from Dicranopteris pedata
《Natural Products and Bioprospecting》2021年第5期557-564,共8页Bei‑Bei Gao Yu‑Fei Ou Qin‑Feng Zhu Zhi‑Ping Zhou Zhen‑Tao Deng Meng Li Qin‑Shi Zhao 
Three new clerodane-type diterpene glycosides,(5R,6S,8R,9S,10R)-6-O-[β-d-glucopyranosyl-(1→4)-α-l-rhamnopyranosyl]cleroda-3,13(16),14-diene(1),(5R,6S,8R,9S,10R,13S)-6-O-[β-d-glucopyranosyl-(1→4)-α-l-rhamnopyrano...
关键词:Dicranopteris pedata Clerodane-type diterpene glycosides ECD 
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