Furanocembranoid from the Okinawan soft coral Sinularia sp.  

作　　者：Misaki Nagasaka Kazuki Tani Keisuke Nishikawa Riri Kinjo Takahiro Ishii 

机构地区：[1]Department of Biosciences and Biotechnology,Faculty of Agriculture,University of the Ryukyus,Senbaru 1,Nishihara,Okinawa 903-0213,Japan [2]Department of Chemistry,Graduate School of Science,Osaka City University,Osaka 558-8585,Japan

出　　处：《Natural Products and Bioprospecting》2022年第1期71-77,共7页应用天然产物（英文）

摘　　要：One new furanocembranoid diterpene,11-hydroxy-Δ^(12(13))-pukalide(1),along with six known secondary metabolites,11-acetoxy-Δ^(12(13))-pukalide(2),13α-acetoxypukalide(3),pukalide(4),3α-methoxyfuranocembranoid(5),Δ9(15)-africanene(6),and methyl(5′E)-5-(2′,6′-dimethylocta-5′,7′-dienyl)furan-3-carboxylate(7)were isolated from the Okinawan soft coral Sinularia sp.Their chemical structures were elucidated based on spectroscopic analysis(FTIR,NMR,and HRESIMS),and the relative stereochemistry of 1 was determined by NOESY experiments and acetylation,which yielded derivative 2.In addition,compounds 1 and 7 exhibited toxicity in the brine shrimp lethality test.

关 键 词：Soft coral Sinularia sp. Furanocembranoid DITERPENE 

分 类 号：O62[理学—有机化学]