多原发大肠癌32例分析  

Diagnosis and Treatment of Multiple Primary Colorectal Carcinoma(Report of 32 Cases)

作　　者：李嘉根[1] 王常标[1] 王卫军[1] 陈国富[1] 李智涛[1] 

机构地区：[1]浙江省温州医学院附属温岭医院外科,温岭317500

出　　处：《中国中西医结合外科杂志》2008年第2期89-91,共3页Chinese Journal of Surgery of Integrated Traditional and Western Medicine

摘　　要：目的:探讨多原发大肠癌的临床特点及诊断治疗。方法:回顾性分析32例多原发大肠癌的临床资料。结果:32例占同期大肠癌的3.75%(32/853),同时性、异时性多原发癌的术前诊断率为61.9%(13/21)、81.8%(9/11);同时性多原发癌术后5年生存率为44.4%(8/18),异时性多原发癌的第1癌术后5年生存率为63.6%(7/11),再发癌术后5年生存率为50%(4/8)。结论:提高对多原发大肠癌的警惕性,术前全面检查,术中仔细探查及常规解剖标本,术后肠镜复查,积极治疗,可提高生存率。Objective To investigate the clinical features, diagnosis and treatment of multiple primary colorectal carcinoma. Methods Thirty-two cases of multiple primary colorectal carcinoma admitted from Mar 1990 to Mar 2001 were analyzed retrospectively. Results The series contains 32 eases, which is about 3.75% （32/853） of the colorectal carcinoma eases admitted in the same period. The postoperative pathologic reports proved that in these eases, 21 cases were synchronous carcinoma, while the other 11 cases were metachronous carcinoma;and 20 eases even accompanied with adenoma（62.5% ）. The preoperative diagnostic rate of synchronous and metachronous carcinoma were 61.9% （13/21） and 81.8% （9/11） respectively. The 5-year survival rate after operation of synchronous and metachronous carcinoma were 44.4%（8/18） and 63.6%（7/11） respectively. And the 5-year survival rate of the recurrent carcinoma was 50% （4/8）. Conclusion The development of multiple primary eolorectal carcinoma should be allerted. A complete prepeerative examination, careful intraoperative explgrafion, routine dissection of specimen, postoperative enteroscopic exam, and active surgical treatment should be emphasized to improve the outcome rate.

关 键 词：多原发大肠癌 诊断 治疗 

分 类 号：R735.34[医药卫生—肿瘤]