温度及pH敏感N-异丙基丙烯酰胺/β-环糊精水凝胶的辐射制备及其性能研究  

Radiation preparation and characterization of temperature-and pH-sensitive hydrogel of N-isopropylacrylamide/β-cyclodextrin copolymer

作　　者：单廷[1] 陈捷[1] 杨黎明[1] 钱锵[1] 揭少卫[1] 林汉[1] 范金辰[1] 曹芳琦[1] 

机构地区：[1]上海大学环境与化学工程学院,上海201800

出　　处：《辐射研究与辐射工艺学报》2008年第2期103-107,共5页Journal of Radiation Research and Radiation Processing

基　　金：上海市第二重点学科(T0105)资助

摘　　要：采用顺丁烯二酸酐(MAH)对β-环糊精(β-CD)进行改性,合成了丁烯二酸单酯化β-环糊精(MAH-β-CD)。以电子束为辐射源对MAH-β-CD和N-异丙基丙烯酰胺(NIPAAm)混合物水溶液进行辐照,制备了Poly(NIPAAm-co-MAH-β-CD)水凝胶。研究了辐照剂量对水凝胶溶胀性能的影响;同时研究了温度、pH值和离子强度等因素对水凝胶溶胀率的影响。结果表明,poly(NIPAAm-co-MAH-β-CD)水凝胶具有温度敏感性、pH敏感性和离子强度敏感性。A hydrogel copolymer of N-isopropylacrylamide/β-cyclodextrin was prepared by radiation copoly- merization method. β-cyclodextrin （β-CD） based monomer （MAH-β-CD） containing vinyl and carboxyl functional groups was synthesized by modification of β-CD with maleic anhydride （MAH）. And then the mixture aqueous solution of NIPAAm and MAH-β-CD was irradiated by electron beams with BIS as cross-linking agent for sample of poly （NIPAAm-co-MAH-β-CD） hydrogel. The effects of temperature, pH and ionic strength on swelling ratio of the hydrogel were determined meanwhile the effect of irradiation absorbed doses on its swelling and deswelling properties was also described. Experimental results show that the copolymer hydrogel possesses temperature, pH and ionic strength sensitive functions.

关 键 词：Β-环糊精 N-异丙基丙烯酰胺 辐射聚合 水凝胶 温度敏感性 PH敏感性 

分 类 号：O631[理学—高分子化学] O632[理学—化学]