树状大分子作为药物载体的研究新进展  

Progress in Study on Dendrimers as Drug-carriers

作　　者：唐杨[1] 马丽芳[1] 郭丽[2] 贺世超[1] 游小杰[1] 

机构地区：[1]四川大学化学工程学院,成都610065 [2]四川大学华西药学院,成都610041

出　　处：《材料导报》2008年第4期100-103,共4页Materials Reports

基　　金：国家自然科学基金资助项目(No.20472055)

摘　　要：树状大分子作为药物载体是目前分子药剂学研究的热点。综述了树状大分子作为药物载体发展的几个阶段、载药方式,以及其作为药物载体在增溶、缓释、靶向等方面的应用,展望了树状大分子作为药物载体的发展趋势。Dendrimers as drug-carders are hot in the current pharmaceutical research. This article provides a review of several stages of the development of dendrimers as drug-carriers, and their ways as well as main applications in solubilization, sustained and targeting release in pharmacy. At last the article points out the prospect of development trends of dendrimers as drug-carders.

关 键 词：树状大分子 药物载体 增溶 缓释 靶向 

分 类 号：R944.9[医药卫生—药剂学]