MRI三维动态增强减影技术早期增强形态对乳腺癌的诊断价值  

Breast Cancer:The Early Enhanced Morphology in Three Dimensional Dynamic Contrast-Enhanced and Digital Subtraction MRI

作　　者：钱吉芳[1] 马强华[2] 叶建军[2] 杨晓萍[2] 陈纲[2] 罗樱[2] 朱晓华[2] 

机构地区：[1]兰州大学临床医学院,甘肃兰州730000 [2]兰州军区兰州总医院影像诊断中心MR室

出　　处：《实用放射学杂志》2008年第4期530-533,共4页Journal of Practical Radiology

摘　　要：目的探讨乳腺MRI三维动态增强减影技术早期增强形态对乳腺癌的诊断价值。方法分析46例52个病灶经手术病理证实的乳腺肿瘤MRI资料,46例术前均行MRI三维动态增强扫描、减影成像。在早期增强率、峰值时间、时间-信号强度曲线、血管纠集等诊断指标的基础上,评价病灶早期增强形态对乳腺癌的诊断价值。结果37个恶性病灶中31个病灶强化时由边缘向中央强化(83.8%,31/37),15个良性病灶中14个病灶由中央向边缘强化(93.3%,14/15)。乳腺癌最特异性征象为MRI动态增强扫描早期环形强化,中后期造影剂由边缘向中央充填,即充填型环形强化,其诊断敏感性为97.3%,特异性为93.3%,准确率为96.2%。结论乳腺MRI动态增强扫描病灶早期强化形态学特征对乳腺癌的诊断有重要意义。Objective To study the value of the early enhanced morphology in three dimensional dynamic contrast - enhanced and digital subtraction MRI in diagnosing breast cancer. Methods Three dimensional dynamic contrast - enhanced and digital subtraction MRI of breast neoplasm in 46 patients（52 lesions） verified by histopathology were performed before operations. MR imaging data were analysed. On the base of early - phase enhanced rate, peak time,blood vessel morphology and time - signal intensity curve, the diagnostic values of the early enhanced morphology of lesions were evaluated. Results In the 37 malignant breast lesions,31 lesions were enhanced from the center to the margin （83.8% ,31/37 ） , 14 benign breast lesions were enhanced from the margin to the center（ 93. 3% , 14/15 ）. The special features of breast cancer in three dimensional dynamic contrast - enhanced and digital subtraction MRI were circular enhancement and the contrast medium filled from the margins to the centre of lesions in middle - later phase , its diagnostic sensitivity , specificity and accuracy were 97.3% , 93.3% and 96.2% respectively. Conclusion The morphological features of three dimensional dynamic contrast - enhanced and digital subtraction MRI has obvious advantages in diagnosing breast cancer.

关 键 词：乳腺癌 磁共振成像 动态增强 

分 类 号：R737.9[医药卫生—肿瘤] R445.2[医药卫生—临床医学]