儿童青少年体成分影响因素的双生子研究  

Twin Study on the Influencing Factors to Body Composition of Children and Adolescents

作　　者：何鲜桂[1] 季成叶[1] 李玉玲[2] 张悦[1] 熊敏[1] 陈天娇[1] 

机构地区：[1]北京大学儿童青少年卫生研究所,北京100083 [2]内蒙古师范大学生命科学与技术学院生物系

出　　处：《中国学校卫生》2008年第4期295-296,298,共3页Chinese Journal of School Health

基　　金：国家自然科学基金资助项目(编号:30371223)

摘　　要：目的分析儿童青少年体成分发育指标的遗传度，探讨遗传对儿童青少年体成分发育的影响。方法测量603对6～18岁同性别双生子（单卵双生431对，二卵双生172对）的体重、肱三头肌皮褶厚度、肩胛下皮褶厚度，计算2处皮褶厚度之和、体脂率、体脂量和瘦体重。用组内相关系数法，计算调整年龄后各指标遗传度。结果各指标组内相关系数均为单卵双生子大于二卵双生子，遗传度均在0．72以上，性别差异无统计学意义。体脂率遗传度男为0．77，女为0．73；体脂量男为0．79，女为0．78；瘦体重男为0．87，女为0．86。结论遗传因素对儿童青少年体成分发育起主要控制作用，其影响程度无明显的性别差异。Objective To analyze the heritability of body composition indices in children and adolescents, and to explore the effect of heredity on children and adolescents＇ body composition. Methods A total of 603 twin pairs, 431 monozygotic （ MZ ） and 172 dizygotic （ DZ ） aged 6 to 18 yeats, were investigated. The measurement included weight, triceps skinfold and subseapular skintold. Sum of triceps and subscapular skinfolds, percentage of body fat （ PBF ） , total of body fat （ TBF ） and lean body mass （ LBM ） were caculated. The heritabilities were estimated using intraclass correlation coefficient method from the adjusted data for age. Results The intraclass correlation coefficient was higher in the MZ twins than in the DZ twins, the heritabilities were all above 0.72, and there were no statistical significant differences of sex betwecn them. The heritabilities of PBF were 0.73 in female, 0.77 in male, for TBF were 0.78 and 0.79, for LBM were 0.86 and 0.87. Conclusion Heredity plays a dominant role in the growth and development of child and adoleseent＇s body composition, and there is no sex difference for the heritabilities.

关 键 词：身体成分 因素分析 统计学 双生研究 青少年 

分 类 号：R179[医药卫生—妇幼卫生保健] R339.35[医药卫生—公共卫生与预防医学]