吡喹酮合成研究进展  

Progress of Research on Synthesis of Praziquantel

作　　者：王东升[1] 

机构地区：[1]上海应用技术学院化学工程系,上海200235

出　　处：《化学世界》2008年第4期249-251,共3页Chemical World

摘　　要：吡喹酮是广谱抗寄生虫药物,对各类血吸虫均有杀灭作用。因其具有疗效高、疗程短、毒性小等优点,目前是世界上治疗血吸虫病的首选药物。概述了吡喹酮的主要合成方法,为吡喹酮的合成研究提供依据。Praziquantel is a broad spectrum antiparasitic drug and has remarkable activity against all species of schistosomas.At present,it is the first choice drug for the treatment of schistosomiasis in the world because of the excellent efficacy,short course of treatment and low toxicity.The principal synthetic methods for Praziquantel are summarised.

关 键 词：吡喹酮 血吸虫病 合成方法 

分 类 号：R914.5[医药卫生—药物化学]