不同胃液中一氧化氮水平变化  被引量:6

ANALYSIS OF NITRIC OXIDE LEVEL IN THE GASTRIC JUICE OF PATIENTS WITH DUODENAL ULCER AND CHRONIC GASTRITIS

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作  者:方建珍[1] 高洁生[1] 卢放根[1] 吴小平[1] 刘德良[1] 

机构地区:[1]湖南医科大学第二附属医院中心实验室

出  处:《胃肠病学和肝病学杂志》1997年第2期116-118,共3页Chinese Journal of Gastroenterology and Hepatology

摘  要:目的:研究十二指肠球部溃疡和慢性浅表性胃炎患者胃液的NO水平,以及胃液NO水平与幽门螺杆菌(HP)感染的可能联系。方法:通过胃镜,抽取23例十二指肠球部溃疡患者、21例慢性浅表性胃炎患者和19例正常人的胃液。用Gries法测胃液中NO水平。结果:十二指肠球部溃疡患者胃液NO水平是(35.56±6.15μmol/L),HP感染者是(34.12±8.10μmol/L)。两者显著高于正常个体(18.60±3.07μmol/L)。慢性浅表性胃炎患者(19.73±2.32μmol/L)和HP阴性者(20.26±3.44μoml/L)胃液中NO水平(P<0.01)。结论:结果提示NO可能是引起十二指肠球部溃疡的一个因素。Aims:To study the nitric oxide(no) level in gastric juice of patients with duodenal ulcer and chronic superficial gastritis and the possible relation of NO in gastric juice and HP infection.Methods:The gastric juice were taken from 23 patients with duodenal ulcer,21 chronic superficial gastritis and 19 healthy individual through the endoscope,NO level in gastric juice was measured by Griess method.Results:The results showed that NO levels in gastric juice of the patients with duodenal ulcer(35.56±6.15 umol/L) and with Hp positive(34.12±8.10 umol/L)were significantly higher than those of healthy individuals(18.60±3.07 umol/L),the patients with chronic superfical gastritis(19.73±2.32umol/L) and HP negative(20.26±3.44umol/L)(P<0.01)Conclusion:The results suggested that NO could be a factr for causing the duodenol ulcer,Hp infection may be the cause of NO elevation in the gastric juice.

关 键 词:一氧化氮 胃液 十二指肠溃疡 浅表性胃炎 

分 类 号:R573[医药卫生—消化系统]

 

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