中西医结合与单纯性激素治疗围绝经期抑郁症  

Therapeutic effect of integrated traditional and western medicine on female perimenopausal depression

作　　者：熊辉[1] 张倩平[1] 陶玉玲[1] 汤翔群[1] 关红[1] 

机构地区：[1]江西省妇幼保健院门诊,南昌330006

出　　处：《中国生育健康杂志》2008年第2期76-78,共3页Chinese Journal of Reproductive Health

摘　　要：目的观察中西医结合戊酸雌二醇和安宫黄体酮片与戊酸雌二醇和安宫黄体酮片(简称性激素治疗组)治疗围绝经期抑郁症的疗效。方法符合围绝经期抑郁症诊断的患者中西医结合治疗组32例,性激素治疗组30例,2组均于治疗前、治疗3个月后各随访1次,应用汉密尔顿抑郁量表(HAMD)评价抑郁症程度;应用Kupperman绝经指数(KMI)评价围绝经症状,并检测FSH和E2水平。结果治疗前2组HAMD、KMI评分及治疗前和治疗后2组FSHT和E2水平比较,差异无统计学意义(P>0.05);治疗3个月后中西医结合治疗组HAMD和KMI评分及疗效高于性激素治疗组,差异有统计学意义意义(P<0.01)。结论中西医结合治疗围绝经期抑郁症的效果及改善围绝经期症状均明显优于单纯性激素治疗组。Objective The purpose of this study is to evaluate the therapeutic effect of integrated traditional Chinese treatment and FSH, in comparison with FSH alone, on perimenopausal depression. Methods Sixty - two women with perimenopausal depression were randomly divided into two group. The in-tegrated group were treated with FSH in combination with traditional Chinese medicine （n = 32）. The FSH group were treated FSH alone （ n = 30）. They were followed - up before treatment, and three months after treatment. Depression was evaluated by HAMD, and perimenopausal symptoms were evaluated by KMI. Results There were no differences in the scores of HAMD and KMI between the two groups before treatment （ P 〉0. 05 ）. However, the scores of HAMD and KMI had significant difference three months after treatment （ P 〈 O. O1 ）, with the integrated group showing greater improvement. Conclusion The integrated therapy seems better than FSH alone in treating perimenopausal depressions.

关 键 词：围绝经期 抑郁症 性激素 中西医结合 

分 类 号：R749.4[医药卫生—神经病学与精神病学]