解偶联蛋白及其基因多态性与能量代谢  

Uncoupling Protein and Polymorphism Regulation the Energy Metabolism

作　　者：文生萍[1] 张丽春 曹振辉[1] 李琦华[1] 田允波[3] 柴艳[1] 陈宝定[1] 葛长荣[1] 贾俊静[1] 

机构地区：[1]云南农业大学动物科学学院,昆明650201 [2]云南省红河州畜牧兽医站,蒙自661100 [3]仲恺农业技术学院生命科学学院,广州510225

出　　处：《中国畜牧兽医》2008年第4期42-45,共4页China Animal Husbandry & Veterinary Medicine

基　　金：云南省自然基金项目(2003C0048M,2006C0033Q);云南农业大学博士启动基金

摘　　要：解偶联蛋白(uncoupling proteins,UCPs)是线粒体内膜蛋白质,目前已至少发现有5种(UCP1、UCP2、UCP3、UCP4和UCP5),这个家族的蛋白质已经在人类、哺乳动物、禽类、鱼,甚至在植物的不同组织线粒体的内膜上被发现。UCPs具有调节能量代谢,促进脂肪酸的氧化作用,UCPs的基因多态性与脂肪代谢相关。The uncoupling proteins are now known to be mitochondrial inner membrane proteins. Recently, more than five family members have been identified including UCP1, UCP2, UCP3, UCP4 and UCP5 in the mitochondrial inner membrane of different tissues and organs of species, such as in human, mammals, poultry, fish and even in plants. UCPs regulate the energy metabolism, increase the fatty acids oxidation and the UCPs polymorphism are related to fat metabolism.

关 键 词：解偶联蛋白 线粒体 基因多态性 能量代谢 

分 类 号：Q591.2[生物学—生物化学]