距肛缘5～8cm直肠癌保肛和非保肛术的疗效比较  

A comparison of sphincter saving operation with abdominoperineal resection in low and middle rectal carcinoma

作　　者：江勃年[1] 张次秀[1] 曾福华[1] 

机构地区：[1]湖南省肿瘤医院腹外科

出　　处：《中国普通外科杂志》1997年第5期259-261,共3页China Journal of General Surgery

摘　　要：１９８４年１月～１９９０年１２月对１４５例距肛缘５～８ｃｍ的直肠癌病例做了根治性切除。其中保肛组６９例，非保肛组７６例。两组病理各期之间比较无统计学差别（Ｐ＞０．０５），组织学类型除高分化腺癌保肛组明显高于非保肛组外（Ｐ＜０．０５），其余各类型相比无统计学差别（Ｐ＞０．０５）。局部复发率和远处转移率保肛组为１４５％和１４５％，非保肛组为１７１％和１８４％，两组之间无统计学差别（Ｐ＞００５）。５年生存率保肛组７９％，非保肛组６７％，两组有统计学差别（Ｐ＜００５），以上资料提示，距肛缘５～８ｃｍ的直肠癌选择分化程度较高、体积小、浸润较浅和淋巴结转移少的病例行保留肛门的根治术，可以提高病人的生存质量和生存期。From January 1984 to December 1990, 145 cases of the low and middle rectal carcinoma (from anal verge is 5～8cm) were treated with radical sphincter saving operation (SSO) or abdominoperineal resection (APR) in Hunan Tumor Hospital. There were 69 patients in SSO group and 76 patients in APR group The ratio of Dukes stages between these two groups was not significantly different ( P >0 05) The histological types in these two groups were not significantly different, except that there were more well differentiated adenocarcinoma in SSO group than that in APR group ( P <0 05) The follow up data showed that the pelvic recurrence and distant metastasis between the two groups (14 5%,14.5% in SSO group and 17.1%,18.4% in APR group respectively) were not significant ( P >0 05). However,the 5 years survival rate (79% in SSO,67% in APR) was significantly different (P<0 05 ) The data suggest that the outcome, both in survival or in quality of life,of SSO is better than that of APR on condition that the cases are properly selected

关 键 词：直肠肿瘤 癌 保肛术 非保肛术 治疗 

分 类 号：R735.370.5[医药卫生—肿瘤]