Effect of thermal cutaneous stimulation on the gastric motor activity:Study of the mechanism of action  

作　　者：Ahmed Shafik Ali A Shafik Olfat El Sibai Ismail A Shafik 

机构地区：[1]Department of Surgery and Experimental Research, Faculty of Medicine, Cairo University, Cairo 11121, Egypt [2]Department of Surgery, Faculty of Medicine, Menoufia University, Shebin El-Kom, Egypt

出　　处：《World Journal of Gastroenterology》2008年第14期2226-2229,共4页世界胃肠病学杂志（英文版）

摘　　要：AIM:To investigate the mechanism of action of thermal cutaneous stimulation on the gastric motor inhibition. METHODS:The gastric tone of 33 healthy volunteers (20 men, mean age 36.7 ± 8.4 years) was assessed by a barostat system consisting of a balloon-ended tube connected to a strain gauge and air-injection system. The tube was introduced into the stomach and the balloon was inflated with 300 mL of air. The skin temperature was elevated in increments of 3℃ up to 49℃ and the gastric tone was simultaneously assessed by recording the balloon volume variations expressed as the percentage change from the baseline volume. The test was repeated after separate anesthetization of the skin and stomach with lidocaine and after using normal saline instead of lidocaine. RESULTS:Thermal cutaneous stimulation resulted in a significant decrease of gastric tone 61.2% ± 10.3% of the mean baseline volume. Mean latency was 25.6 ± 1.2 ms. After 20 min of individual anesthetization of the skin and stomach, thermal cutaneous stimulation produced no significant change in gastric tone. CONCLUSION:Decrease in the gastric tone in response to thermal cutaneous stimulation suggests a reflex relationship which was absent on individual anesthetization of the 2 possible arms of the reflex arc:the skin and the stomach. We call this relationship the"cutaneo-gastric inhibitory reflex". This reflex may have the potential to serve as an investigative tool in the diagnosis of gastric motor disorders, provided further studies are performed in this respect.AIM：To investigate the mechanism of action of thermal cutaneous stimulation on the gastric motor inhibition. METHODS：The gastric tone of 33 healthy volunteers （20 men, mean age 36.7 ± 8.4 years） was assessed by a barostat system consisting of a balloon-ended tube connected to a strain gauge and air-injection system. The tube was introduced into the stomach and the balloon was inflated with 300 mL of air. The skin temperature was elevated in increments of 3℃ up to 49℃ and the gastric tone was simultaneously assessed by recording the balloon volume variations expressed as the percentage change from the baseline volume. The test was repeated after separate anesthetization of the skin and stomach with lidocaine and after using normal saline instead of lidocaine. RESULTS：Thermal cutaneous stimulation resulted in a significant decrease of gastric tone 61.2% ± 10.3% of the mean baseline volume. Mean latency was 25.6 ± 1.2 ms. After 20 min of individual anesthetization of the skin and stomach, thermal cutaneous stimulation produced no significant change in gastric tone. CONCLUSION：Decrease in the gastric tone in response to thermal cutaneous stimulation suggests a reflex relationship which was absent on individual anesthetization of the 2 possible arms of the reflex arc：the skin and the stomach. We call this relationship the＂cutaneo-gastric inhibitory reflex＂. This reflex may have the potential to serve as an investigative tool in the diagnosis of gastric motor disorders, provided further studies are performed in this respect.

关 键 词：Gastric tone BAROSTAT Gastric disorders 

分 类 号：R573[医药卫生—消化系统]