迷迭香提取物的抗肿瘤作用  

Antitumor efficacy of extract of Rosmarinus officinalis

作　　者：孙权[1] 崔长旭[1] 全吉淑[1] 沈明花[1] 

机构地区：[1]延边大学医学部,延吉133000

出　　处：《食品科技》2008年第4期156-158,共3页Food Science and Technology

摘　　要：目的:研究迷迭香乙醇提取物对人肺癌细胞株A549、肝癌细胞株SMMC7721的生长抑制作用。方法:分别用HE染色法和溴化二苯偶氮盐(MTT)检测法,观察其形态学变化和对肿瘤细胞的增殖抑制作用。结果:显微镜下可见A549、SMMC7721形态明显改变,200 mg/mL迷迭香提取物作用48h时,其抑制率分别为(93.06±1.56)%、(84.39±1.96)%。结论:迷迭香提取物对A549、SMMC7721细胞均有抑制作用,且呈量效关系。Objective：To investigate the cytotoxic effect of Rosmarinus officinalis L. extract on human lung carcinoma A549 and hepatoma SMMC7721. Method.The morphology was observed with HE staining, the inhibitory effect on cell proliferation of A549 and SMMC7721 was used MTT assay. Result：The morphology of A549 and SMMC7721 significantly changed under light microscope. The inhibitory rate is （93.06-1.56）% and（84.39-1.96）%, respectively for A549 and SMMC7721 at 48 h at the concentration of 200 mg/mL. Conclusion： The extract of Rosmarinus officinalis L. had inhibitory effect on the proliferation of A549 and SMMC7721, the effect was dose dependent.

关 键 词：迷迭香 抗肿瘤 抑制 

分 类 号：TS201.3[轻工技术与工程—食品科学]