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机构地区:[1]安阳市肿瘤医院妇科
出 处:《河南肿瘤学杂志》1997年第5期367-368,共2页Henan Journal of Oncology
摘 要:1978年1月~1990年1月,我院对60例卵巢上皮癌合并腹水进行腹腔化疗,其中Ⅰ期19例,Ⅱ期14例,Ⅲ期27例。初治时先行手术治疗,确定临床分期及病理分类,之后给予腹腔化疗。所用药物为:MMC6mg+5-Fu500~750mg+AT125840~60mg,每周用药1次。60例化疗2~13次,平均5次。化疗4次以上3年5年存活率明显高于化疗3次以下者。提示多疗程腹腔化疗能提高卵巢癌合并腹水的生存率。From January 1978 to January 1990,60 cases of ovarian epithelial carcinoma including 19 cases of stage Ⅰ, 14 cases of stage Ⅱ, and 27 cases of stages Ⅲ were treated with intraperineal chemotherapy.Each stage was first operated to confirm clinical stages and pathelogic types,then beated with intraperitoneal chemotheropy. The drugs were MMC 6mg, 5 - FU 500 ~ 750mg and AT1258 40 ~ 60mg. We used them once a wddk. The patients received the treatment from 2 to 13 times and had 5 times on an average.The survival rates of 3 to 5 years of the patients being treated more than 4 times were much higher than those of the Patients being treated less than 3 times. It suggests that multipule courses of intraperitoneal chemotherapy can improve the survival late of Patients with ovarian carcinoma with ascites.
分 类 号:R737.310.5[医药卫生—肿瘤]
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