双相抑郁与单相抑郁临床相关特征差异的Meta分析  

Meta-analysis of Difference of Relative Clinical Traits between Bipolar and Unipolar Depression

作　　者：张耀锋[1] 金卫东[1] 陈炯[1] 邢葆平[1] 唐贤祥[1] 王鹤秋[1] 马永春[1] 

机构地区：[1]浙江省立同德医院精神科,浙江省精神卫生研究院,浙江省杭州市310012

出　　处：《中国全科医学》2008年第10期846-848,共3页Chinese General Practice

基　　金：浙江省卫生厅医药科技资助项目(2003B024)

摘　　要：目的了解双相抑郁与单相抑郁的一般临床特征的差异。方法应用Meta分析对国内符合标准的13项研究进行分析,比较双相抑郁与单相抑郁一般特征的差异及差异的效应大小。结果双相抑郁与单相抑郁患者在躯体问题、年龄、发病年龄、发作次数、复发率、病程、预后或疗效方面差异有统计学意义(P<0·05)。结论双相抑郁与单相抑郁有某些特征的差异,这些差异可能对临床鉴别抑郁症的类型有一定的意义。Objective To understand the differences in general traits between bipolar and unipolar depression. Methods The difference and it＇s effect size were analyzed by Meta - analysis in 13 studies published in domestic journals with a standard of study. Results There were significant differences in the somatic problem, age, the first onset age, time of onset, relapse rate, illness duration and outcome between bipolar depression and unipolar depression （ P 〈0. 05）. Conclusion There is the differences in some general traits between bipolar and unipolar depression, which maybe useful in diagnosis of depression type.

关 键 词：抑郁症 META分析 

分 类 号：R749.42[医药卫生—神经病学与精神病学]