pH敏感丙烯酰胺/β-环糊精水凝胶的辐射制备及其性能研究  

Radiation preparation and characterization of pH-sensitive hydrogel of acrylamide/β-cyclodextrin copolymer

作　　者：单廷[1] 陈捷[1] 杨黎明[1] 揭少卫[1] 钱锵[1] 林汉[1] 范金辰[1] 曹芳琦[1] 

机构地区：[1]上海大学环境与化学工程学院,上海201800

出　　处：《核技术》2008年第4期284-287,共4页Nuclear Techniques

基　　金：上海市第二期重点学科(T0105)资助

摘　　要：用顺丁烯二酸酐(MAH)对β-环糊精(β-CD)进行化学改性,合成了丁烯二酸单酯化β-环糊精(MAH-β-CD)。采用电子束对MAH-β-CD和丙烯酰胺(AAm)混合水溶液辐照,制得含β-CD结构单元的水凝胶poly(AAm-co-MAH-β-CD)。研究了各组分配比、辐照剂量等对水凝胶性能的影响;测定了pH值和离子强度等因素对水凝胶溶胀率的影响。结果表明,poly(AAm-co-MAH-β-CD)水凝胶具有一定的pH敏感性和离子强度敏感性,在pH<5时,水凝胶的溶胀率较小,pH5～8时,溶胀率快速上升,最后趋于平稳;pH>5时,同一辐照剂量的水凝胶溶胀率随MAH-β-CD含量的增加明显增大,而在相同组分下水凝胶的溶胀率随剂量的增大而下降。A β-cyclodextrin （β-CD） based monomer （MAH-β-CD） containing vinyl and carboxyl functional groups was synthesized by reaction of β-CD with maleic anhydride （MAH）. By copolymerization of the monomer with acrylamide （AAm）, a novel hydrogel, poly （AAm-co-MAH-β-CD） with pH and ionic strength sensitivities plus molecular inclusion function, was obtained by irradiating the aqueous solution mixture of AAm and MAH-β-CD with electron beam. The effect of the feed ratio of components and irradiation dose on the swelling and deswelling properties of the hydrogel was systematically studied. Swelling ratio of the hydrogel was tested under different environment of pH and ionic strength. The results indicate that the copolymer hydrogels did not show any noticeable change in swelling at lower pH （pH〈5）. However, they showed an abrupt increase in swelling at pH 5-8 due to the ionization of carboxyl groups.

关 键 词：Β-环糊精 丙烯酰胺 辐照 水凝胶 PH敏感性 离子强度敏感性 

分 类 号：O63[理学—高分子化学]