猪传染性胸膜肺炎放线杆菌溶血素的研究进展  

Research Progress on RTX-toxins of porcine Actinobacillus pleuropneumoniae

作　　者：马艳芳[1] 张鑫[1] 张瑞平[1] 刘方娜[1] 刁有祥[1] 

机构地区：[1]山东农业大学动物科技学院,山东泰安271018

出　　处：《福建农业学报》2008年第1期111-115,共5页Fujian Journal of Agricultural Sciences

基　　金：山东省中青年科学家科研奖励基金(2007BS06004)

摘　　要：猪传染性胸膜肺炎是由胸膜肺炎放线杆菌引起的一种呼吸道疾病。根据荚膜多糖和脂多糖抗原表位不同,将胸膜肺炎放线杆菌分为15个血清型,不同血清型的菌株毒力大小不同,致病性也有强弱之别。该菌的致病性与多种毒力因子密切相关,而溶血素是决定该病原菌致病性强弱的关键因素。本文主要就其溶血素的研究进展作综述。The contagious porcine pleuropneumonia is a respiratory tract infection in pigs. High occurrence rate of the disease has been reported worldwide. Fifteen serotypes in Actinobacillus pleuropneumoniae （App） are classified based on the cluster positions of the capsular poly-saccharide and lipopolysaccharide antigens. Different App serotypes exhibit different virulence and pathogenicity. There is a close correlation between the virulence factors and pathogenicity of these App serotypes. Among the virulence factors, RTX-toxins are most critical in the determina tion of an App＇s pathogenicity. This article elucidates the progress in the field of study.

关 键 词：传染性胸膜肺炎 放线杆菌 溶血素 

分 类 号：S858[农业科学—临床兽医学]