重症急性胰腺炎多层螺旋CT灌注研究  

The study on multi-spiral CT perfusion for severe acute pancreatitis

作　　者：邵娟[1] 卜平[1] 征锦[2] 孔桂美[1] 

机构地区：[1]扬州大学医学院,扬州225001 [2]江苏省苏北人民医院影像科

出　　处：《中华胰腺病杂志》2008年第2期73-75,共3页Chinese Journal of Pancreatology

基　　金：江苏省自然科学基金项目（BG2006606）

摘　　要：目的探讨SAP的CT灌注特点，评价其临床价值。方法使用16排螺旋CT对9例SAP患者、17例MAP患者以及41例胰腺正常者进行CT灌注扫描。应用perfusion3软件包进行数据处理，计算各组的血流量（BF）、血容量（BV）、平均通过时间（MTr）、毛细血管通透性（IS）等灌注参数，并行独立样本t检验。结果MAP组的BF、BV平均值为（121．5±55．27）ml·100mg^-1·min^-1、（11．7±5．26）ml／100mg，SAP组平均值为（63．58±36．91）ml·100mg^-1·min^-1、（7．13±2．11）ml／100mg，差异显著（P〈0．01）；较正常组的（219．17±98．02）ml·100mg^-1·min^-1和（18．60±14．75）ml／100mg，均显著降低（P〈0．01）。MAP组和SAP组的PS分别为（25．14±10．7）ml·100mg^-1·min^-1和（34．61±11．25）ml·100mg^-1·min^-1，均高于正常组的（16．61±9．36）ml·100mg^-1·min^-1（P〈0．05）。结论CT灌注成像技术判断SAP的严重程度有临床应用价值。Objective To evaluate the characteristics of the CT perfusion for severe acute pancreatitis. Methods We performed CT perfusion scan on three groups of 9, 17and 41 cases with severe, mild and normal pancreatitis respectively, using 16 rows spiral CT, and got the perfusion data of the relevant groups including blood flow （BL）, blood volume（BV）, mean transit time（MTT）, capillary permeability（PS） with perfusion package 3. We analize the data deviation between the groups mentioned above. Furthmore, we still adapt correlation test to compare the clinical biochemical indicators of MAP and SAP, with the variance BF. Results The mean values of BF, BV reduce significally in the groups of MAP, SAP compared to the normal group（P 〈0.01）, only PS goes higher than that of the normal group（P 〈0.05）. At the same time, they are obviously higher in MAP group than in SAP group. In MAP group, the level of blood hemodiastase and BF are negatively correlated, on the contray, in SAP group, the level of the blood hemodiastase has no relation to BF. Conclusions CT peffusion techniques are of great significance in early diagnosis in SAP, and in guiding the clinical therapy.

关 键 词：胰腺炎 急性坏死性 体层摄影术 螺旋计算计 诊断显像 

分 类 号：R576[医药卫生—消化系统] R816.5[医药卫生—内科学]