依达拉奉治疗急性脑梗死疗效评价  

Edaravone In Treatment of Acute Cerebral Infarction

作　　者：冯淑曼[1] 腾军放[1] 

机构地区：[1]郑州大学第一附属医院神经内科

出　　处：《医药论坛杂志》2008年第8期12-13,共2页Journal of Medical Forum

摘　　要：目的评价依达拉奉治疗急性脑梗死的疗效及安全性。方法凡符合入选标准的患者随机分为两组:两组均给予静脉滴注胞二磷胆碱1.0g,qd,银杏叶针20ml,肠溶阿司匹林100mgqd,共14d;治疗组加用依达拉奉30mg,采用欧洲脑卒中量表评价神经功能恢复状况。结果治疗组表评分改善情况优于对照组,两者比较差异有统计学意义(P<0.05),两者均未发生严重不良反应。结论依达拉奉治疗急性脑梗死所致的神经功能缺损效果及安全性良好。Objective To investigate the effectiveness and safety of edaravone for acute cerebral infarction. Methods Total 92 patients were randomly divided into two groups. Patients in each group were given Cytidine Diphos phate Choline 1.0g and Ginkgo Biloba Extract 20ml injection, Aspirin 100mg once per day. The treatment group was given Edaravone injection 30mg twice per day. The treatment was 14 days for both groups. The ESS was used to evaluate the recovery of neurological func- tions. Results ESS increased significantly in study group compared with that ot control group after treatment. No serious drug reaction were found in two groups. Conclusion Edaravone injection is effective and sate in the treatment of acute cerebral infarction.

关 键 词：脑梗死 依达拉奉(必存) 疗效评价 

分 类 号：R743.3[医药卫生—神经病学与精神病学]