内镜热极技术联用抑酸剂治疗Barrett’s食管的临床观察  

Observation of clinical effect on the treatment of Barrett's esophagus by combining heat probe thermocoagulation with taking proton pump inhibitor

作　　者：张汝钢[1] 房殿春[2] 郭先科[1] 钟汉馨[3] 

机构地区：[1]解放军150中心医院消化内科,河南洛阳471031 [2]第三军医大学西南医院全军消化病研究所 [3]解放军150中心医院病理科

出　　处：《胃肠病学和肝病学杂志》2008年第5期370-371,374,共3页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的探讨内镜热极技术联用抑酸剂治疗Barrett’s食管的疗效。方法2006年8月～2007年8月经内镜和病理组织学检查诊断的Barrett’s食管患者100例，其中95例患者在内镜下采用热极治疗，术后口服抑酸剂巩固治疗，另5例患者仅口服抑酸剂治疗进行对照，两组均进行内镜及临床随访。结果95例患者经过1次热极治疗Barrett’s食管完全消除，术后38例（40％）出现胸骨后隐痛；54例患者半年后随访，总有效率为92．59％；对照组3例患者半年后随访，总有效率为0。结论热极联用抑酸剂治疗Barrett’s食管安全有效、短期疗效好。probe thermoc Objective To investigate the therapeutic effect on Barrett＇ s esophagus treatment by combining heat oagulation with taking proton pump inhibitor. Methods One hundred cases Barrett＇s esophagus demonstrated by gastroscopy and histopathologic examination were adopt between August 2006 and August 2007. By methods of combining heat probe thermocoagulation with proton pump inhibitor, 95 cases were treated and followed up. Meanwhile, 5 cases were only treated by proton pump inhibitor and also followed up. Results Barrett＇ s esophagus mucosa was completely eliminated by method of heat probe thermocoagulation. However, retrosternal pain was found in 38/95 cases. Total effective rate was 92.59% after follow-up 6 month to 54 cases. However, total effective rate was only zero after follow-up 6 month to 3/5 cases. Conclusion It is a safe and effective method to treat Barrett＇ s esophagus by using heat probe thermocoagulation and taking proton pump inhibitor. However, long-term effect needs further investigation.

关 键 词：Barrett’s食管 热极技术 内镜下治疗 

分 类 号：R571[医药卫生—消化系统]